Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

Antibiotic resistance and its cost: is it possible to reverse resistance?

DI Andersson, D Hughes - Nature Reviews Microbiology, 2010 - nature.com
Most antibiotic resistance mechanisms are associated with a fitness cost that is typically
observed as a reduced bacterial growth rate. The magnitude of this cost is the main …

Antimicrobial stewardship

S Doron, LE Davidson - Mayo Clinic Proceedings, 2011 - Elsevier
Antimicrobial resistance is increasing; however, antimicrobial drug development is slowing.
Now more than ever before, antimicrobial stewardship is of the utmost importance as a way …

Drug repurposing screens and synergistic drug‐combinations for infectious diseases

W Zheng, W Sun, A Simeonov - British journal of pharmacology, 2018 - Wiley Online Library
Infectious diseases account for nearly one fifth of the worldwide death toll every year. The
continuous increase of drug‐resistant pathogens is a big challenge for treatment of …

Persistence of antibiotic resistance in bacterial populations

DI Andersson, D Hughes - FEMS microbiology reviews, 2011 - academic.oup.com
Unfortunately for mankind, it is very likely that the antibiotic resistance problem we have
generated during the last 60 years due to the extensive use and misuse of antibiotics is here …

Antibiotic prescribing in hospitals: a social and behavioural scientific approach

MEJL Hulscher, RPTM Grol… - The Lancet infectious …, 2010 - thelancet.com
Antibiotics have dramatically changed the prognoses of patients with severe infectious
diseases over the past 50 years. However, the emergence and dissemination of resistant …

Guidance on the selection of appropriate indicators for quantification of antimicrobial usage in humans and animals

L Collineau, C Belloc, KDC Stärk… - Zoonoses and public …, 2017 - Wiley Online Library
An increasing variety of indicators of antimicrobial usage has become available in human
and veterinary medicine, with no consensus on the most appropriate indicators to be used …

[HTML][HTML] Cleaning and disinfecting environmental surfaces in health care: toward an integrated framework for infection and occupational illness prevention

MM Quinn, PK Henneberger, B Braun… - American journal of …, 2015 - Elsevier
Background The Cleaning and Disinfecting in Healthcare Working Group of the National
Institute for Occupational Safety and Health, National Occupational Research Agenda, is a …

Epidemiological interpretation of studies examining the effect of antibiotic usage on resistance

V Schechner, E Temkin, S Harbarth… - Clinical microbiology …, 2013 - Am Soc Microbiol
Bacterial resistance to antibiotics is a growing clinical problem and public health threat.
Antibiotic use is a known risk factor for the emergence of antibiotic resistance, but …

Recommendations for approaches to meticillin‐resistant staphylococcal infections of small animals: diagnosis, therapeutic considerations and preventative measures …

DO Morris, A Loeffler, MF Davis… - Veterinary …, 2017 - Wiley Online Library
Background Multiple drug resistance (MDR) in staphylococci, including resistance to the
semi‐synthetic penicillinase‐resistant penicillins such as meticillin, is a problem of global …