The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

Abstract In 2011, the National Institute on Aging and Alzheimer's Association created
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …

Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Technologies for imaging the pathophysiology of Alzheimer disease (AD) now permit
studies of the relationships between the two major proteins deposited in this disease …

Many human brain disorders are associated with characteristic alterations in the structural
and functional connectivity of the brain. In this article, we explore how commonalities and …

It is currently unclear how amyloid-β and tau deposition are linked to changes in synaptic
function and axonal structure over the course of Alzheimer's disease. Here, we assessed …

Introduction The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

Introduction We performed a systematic review and meta-analysis of the Alzheimer's
disease (AD) literature to examine consistency of functional connectivity alterations in AD …

Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …