Hyperbranched polysiloxane-based probe with enhanced lipophilicity for visualizing ONOO− fluctuations in endoplasmic reticulum

K Zhang, Y Zhang, Y Lan, F Wang, Z Gou, M Yan… - Analytica Chimica …, 2023 - Elsevier
The endoplasmic reticulum, a cellular signaling regulator, participates in the synthesis and
secretion of many proteins, glycogen, lipids and cholesterol substances. Peroxynitrite …

Antimicrobial Photodynamic Therapy for the Remote Eradication of Bacteria

E Yan, G Kwek, NS Qing, S Lingesh, B Xing - ChemPlusChem, 2023 - Wiley Online Library
The emergence of multi‐drug resistant bacteria strains has been an uphill battle in modern
healthcare worldwide, due to the increasing difficulty of killing them. The evolving …

Aryl‐Modified Pentamethyl Cyanine Dyes at the C2'Position: A Tunable Platform for Activatable Photosensitizers

F Han, SA Abbas Abedi, S He, H Zhang… - Advanced …, 2024 - Wiley Online Library
Pentamethyl cyanine dyes are promising fluorophores for fluorescence sensing and
imaging. However, advanced biomedical applications require enhanced control of their …

Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education

Y Huang, Z Guan, L Ren, Y Luo, M Chen, Y Sun… - Journal of Controlled …, 2022 - Elsevier
Chemodynamic therapy (CDT), an emerging tumor-specific therapeutic modality, is
frequently restrained by insufficient intratumoral Fenton catalysts and increasingly inefficient …

Photosensitizers for photodynamic therapy: Structure-activity analysis of cyanine dyes through design of experiments

C Pontremoli, G Chinigò, S Galliano, MJM Plata… - Dyes and …, 2023 - Elsevier
In this work, a new series of pentamethine indolenine cyanine dyes has been designed and
synthesized with the aim to investigate a structure-activity relationship on their photodynamic …

Strengthened EPR effect of AIEgen-Poly (I: C) composite nanoparticles to facilitate antigen cross-presentation and improve melanoma prognosis by evoking immunity

L Yang, X Wang, Y Zhao, Y Li, X Wang, J Deng… - Chemical Engineering …, 2023 - Elsevier
Nanoparticles offer a promising platform for drug delivery due to their long circulation time,
enhanced solubility, low toxicity and excellent targeting of lesions. Herein, we report an …

Visual identification of 1 O 2-induced crystal structure transformation of single Zr-MOF by dark-field microscopy

Y Xu, Q Li, W He, CP Yang, PF Gao, YF Li… - Chemical …, 2023 - pubs.rsc.org
Understanding the structural transformation of photocatalysts under illumination provides
detailed insights to solve the poisoning of photocatalysts. In this study, the 1O2-induced …

Aggregation-Induced emission photosensitizer with lysosomal response for photodynamic therapy against cancer

Z Pan, Y Wang, N Chen, G Cao, Y Zeng, J Dong… - Bioorganic …, 2023 - Elsevier
Photosensitizers play a key role in bioimaging and photodynamic therapy (PDT) of cancer.
However, conventional photosensitizers usually do not achieve the desired efficacy in PDT …

Lutidine derivatives for live-cell imaging of the mitochondria and endoplasmic reticulum

D Singh, DJ Shewale, A Sengupta… - Organic & …, 2022 - pubs.rsc.org
The mitochondria and endoplasmic reticulum (ER) are highly dynamic subcellular structures
essential for several biological functions. The development of non-toxic, wash-free …

Recent Progress in Endoplasmic Reticulum-Targetable Small-Molecule Probes for Fluorescence Sensing and Phototherapy

J Chen, H Liu, W Xie, M Gu, G Mao, S Yang - Journal of Analysis and …, 2023 - Springer
The endoplasmic reticulum (ER) is the most widespread organelle within eukaryotic cells,
performing various essential functions such as protein synthesis, post-translational …