Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and
the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance …

Intestinal fibrosis, which is usually the consequence of chronic inflammation, is a common
complication of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative …

The mammalian gut microbial community which is known as the gut microbiota comprises
trillions of bacteria, which co-evolved with the host and has a vital role in a variety of host …

The capability to design microbiomes with predictable functions would enable new
technologies for applications in health, agriculture, and bioprocessing. Towards this goal …

Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

Culture-independent metagenomic studies have revolutionized our understanding of the gut
microbiota. However, the lack of full genomes from cultured species is still a limitation for in …

Despite milestones in preventive measures and treatment, cardiovascular disease (CVD)
remains associated with a high burden of morbidity and mortality. The protracted nature of …

The intestinal microbiota influences mammalian host physiology in health and disease
locally in the gut but also in organs devoid of direct contact with bacteria such as the liver …