Deep learning based an efficient hybrid prediction model for Covid-19 cross-country spread among E7 and G7 countries
A Utku - Decision Making: Applications in Management and …, 2023 - dmame-journal.org
The COVID-19 pandemic has caused the death of many people around the world and has
also caused economic problems for all countries in the world. In the literature, there are …
also caused economic problems for all countries in the world. In the literature, there are …
[HTML][HTML] Exploring and mitigating potential bias when genetic instrumental variables are associated with multiple non-exposure traits in Mendelian randomization
With the increasing size and number of genome-wide association studies, individual single
nucleotide polymorphisms are increasingly found to associate with multiple traits. Many …
nucleotide polymorphisms are increasingly found to associate with multiple traits. Many …
[HTML][HTML] Schizophrenia-associated differential DNA methylation in brain is distributed across the genome and annotated to MAD1L1, a locus at which DNA …
BC McKinney, LL McClain, CM Hensler, Y Wei… - Translational …, 2022 - nature.com
DNA methylation (DNAm), the addition of a methyl group to a cytosine in DNA, plays an
important role in the regulation of gene expression. Single-nucleotide polymorphisms …
important role in the regulation of gene expression. Single-nucleotide polymorphisms …
Phenotypic causal inference using genome-wide association study data: Mendelian randomization and beyond
Summary statistics for genome-wide association studies (GWAS) are increasingly available
for downstream analyses. Meanwhile, the popularity of causal inference methods has grown …
for downstream analyses. Meanwhile, the popularity of causal inference methods has grown …
Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits
Posttraumatic stress disorder (PTSD) is a psychiatric disorder that may arise in response to
severe traumatic event and is diagnosed based on three main symptom clusters …
severe traumatic event and is diagnosed based on three main symptom clusters …
[HTML][HTML] Fast and flexible joint fine-mapping of multiple traits via the Sum of Single Effects model
We introduce mvSuSiE, a multi-trait fine-mapping method for identifying putative causal
variants from genetic association data (individual-level or summary data). mvSuSiE learns …
variants from genetic association data (individual-level or summary data). mvSuSiE learns …
[HTML][HTML] Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease
More than 240 genetic risk loci have been associated with inflammatory bowel disease
(IBD), but little is known about how they contribute to disease development in involved …
(IBD), but little is known about how they contribute to disease development in involved …
[PDF][PDF] Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: lessons from the Global Biobank Meta-analysis Initiative
Summary The Global Biobank Meta-analysis Initiative (GBMI), through its diversity, provides
a valuable opportunity to study population-wide and ancestry-specific genetic associations …
a valuable opportunity to study population-wide and ancestry-specific genetic associations …
[PDF][PDF] Smoking, DNA methylation, and lung function: a mendelian randomization analysis to investigate causal pathways
E Jamieson, R Korologou-Linden, RE Wootton… - The American Journal of …, 2020 - cell.com
Whether smoking-associated DNA methylation has a causal effect on lung function has not
been thoroughly evaluated. We first investigated the causal effects of 474 smoking …
been thoroughly evaluated. We first investigated the causal effects of 474 smoking …
Identifying cross-disease components of genetic risk across hospital data in the UK Biobank
Genetic risk factors frequently affect multiple common human diseases, providing insight into
shared pathophysiological pathways and opportunities for therapeutic development …
shared pathophysiological pathways and opportunities for therapeutic development …