Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management

ZH McMahan, S Kulkarni, J Chen, JZ Chen… - Nature Reviews …, 2023 - nature.com
Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the
gastrointestinal tract, and the severity of gastrointestinal disease in SSc correlates with high …

Molecular cell types as functional units of the efferent vagus nerve

TC Coverdell, SBG Abbott, JN Campbell - Seminars in Cell & …, 2023 - Elsevier
The vagus nerve vitally connects the brain and body to coordinate digestive,
cardiorespiratory, and immune functions. Its efferent neurons, which project their axons from …

Development and regeneration of the vagus nerve

AJ Isabella, CB Moens - Seminars in Cell & Developmental Biology, 2023 - Elsevier
The vagus nerve, with its myriad constituent axon branches and innervation targets, has
long been a model of anatomical complexity in the nervous system. The branched …

[HTML][HTML] Retinoic acid organizes the zebrafish vagus motor topographic map via spatiotemporal coordination of Hgf/Met signaling

AJ Isabella, GR Barsh, JA Stonick, J Dubrulle… - Developmental cell, 2020 - cell.com
Information flow through neural circuits often requires their organization into topographic
maps in which the positions of cell bodies and synaptic targets correspond. To understand …

Developmental and molecular contributions to contextual fear memory emergence in mice

AL Lanjewar, P Levitt, KL Eagleson - Neuropsychopharmacology, 2024 - nature.com
Cognitive impairment is a common phenotype of neurodevelopmental disorders, but how
these deficits arise remains elusive. Determining the onset of discrete cognitive capabilities …

Subclass‐specific expression patterns of MET receptor tyrosine kinase during development in medial prefrontal and visual cortices

AL Lanjewar, S Jagetia, ZM Khan… - Journal of …, 2023 - Wiley Online Library
Met encodes a receptor tyrosine kinase (MET) that is expressed during development and
regulates cortical synapse maturation. Conditional deletion of Met in the nervous system …

The parasympathetic and sensory innervation of the proximal and distal colon in male mice

L Wang, Y Taché - Frontiers in Neuroanatomy, 2024 - frontiersin.org
Introduction The distributions of extrinsic neurons innervating the colon show differences in
experimental animals from humans, including the vagal and spinal parasympathetic …

Developmental connectivity and molecular phenotypes of unique cortical projection neurons that express a synapse-associated receptor tyrosine kinase

RJ Kast, HH Wu, P Levitt - Cerebral Cortex, 2019 - academic.oup.com
The complex circuitry and cell-type diversity of the cerebral cortex are required for its high-
level functions. The mechanisms underlying the diversification of cortical neurons during …

Control of cortical synapse development and plasticity by MET receptor tyrosine kinase, a genetic risk factor for autism

X Ma, S Qiu - Journal of neuroscience research, 2020 - Wiley Online Library
The key developmental milestone events of the human brain, such as neurogenesis,
synapse formation, maturation, and plasticity, are determined by a myriad of molecular …

MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development

AK Kamitakahara, R Ali Marandi Ghoddousi… - Frontiers in …, 2021 - frontiersin.org
The intrinsic muscles of the larynx are innervated by the vagal motor nucleus ambiguus
(nAmb), which provides direct motor control over vocal production in humans and rodents …