Hamster models of COVID-19 pneumonia reviewed: How human can they be?

AD Gruber, TC Firsching, J Trimpert… - Veterinary …, 2022 - journals.sagepub.com
The dramatic global consequences of the coronavirus disease 2019 (COVID-19) pandemic
soon fueled quests for a suitable model that would facilitate the development and testing of …

Pathophysiology and clinical management of coronavirus disease (COVID-19): a mini-review

Y Zhu, L Sharma, D Chang - Frontiers in Immunology, 2023 - frontiersin.org
An unprecedented global pandemic caused by a novel coronavirus named SARS-CoV-2
has created a severe healthcare threat and become one of the biggest challenges to human …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

Factors associated with COVID-19 vaccine response in transplant recipients: a systematic review and meta-analysis

J Li, I Ayada, Y Wang, CM den Hoed, N Kamar… - …, 2022 - journals.lww.com
Background. The rapid development and universal access to vaccines represent a
milestone in combating the coronavirus disease 2019 (COVID-19) pandemic. However …

Increased kynurenine indicates a fatal course of COVID-19

H Mangge, M Herrmann, A Meinitzer, S Pailer, P Curcic… - Antioxidants, 2021 - mdpi.com
(1) Background: An inefficient immune response accompanied by an overwhelming
inflammatory reaction is involved in severe courses of COVID-19. Kynurenine (KYN) has …

Comparison between the first and second COVID-19 waves in Internal Medicine wards in Milan, Italy: a retrospective observational study

D Blanca, S Nicolosi, A Bandera, F Blasi… - Internal and Emergency …, 2022 - Springer
COVID-19 spread in two pandemic waves in Italy between 2020 and 2021. The aim of this
study is to compare the first with the second COVID-19 wave, analyzing modifiable and non …

The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling

E Laplantine, C Chable-Bessia, A Oudin, J Swain… - Iscience, 2022 - cell.com
Patients with severe COVID-19 show an altered immune response that fails to control the
viral spread and suffer from exacerbated inflammatory response, which eventually can lead …

Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality

Y Chen, J Sun, H Tong, J Wang, R Cao… - Journal of Medicinal …, 2024 - ACS Publications
Epoxyeicosatrienoic acids with anti-inflammatory effects are inactivated by soluble epoxide
hydrolase (sEH). Both sEH and histone deacetylase 6 (HDAC6) inhibitors are being …

Type 2 diabetes contributes to altered adaptive immune responses and vascular inflammation in patients with SARS-CoV-2 infection

M Singh, O Barrera Adame, M Nickas… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2, which initially emerged in November of 2019, wreaked havoc across the
globe by leading to clinical acute respiratory distress syndrome and continues to evade …

[HTML][HTML] SMART for the treatment of asthma: a network meta-analysis of real-world evidence

P Rogliani, R Beasley, M Cazzola, L Calzetta - Respiratory Medicine, 2021 - Elsevier
A large proportion of asthmatic patients are treated with protocols resulting from data
obtained by randomized controlled trials (RCTs) for which they would not have been …