The remarkable frequency of human immunodeficiency virus type 1 genetic recombination

A Onafuwa-Nuga, A Telesnitsky - Microbiology and Molecular …, 2009 - Am Soc Microbiol
The genetic diversity of human immunodeficiency virus type 1 (HIV-1) results from a
combination of point mutations and genetic recombination, and rates of both processes are …

[HTML][HTML] Viral population estimation using pyrosequencing

N Eriksson, L Pachter, Y Mitsuya, SY Rhee… - PLoS computational …, 2008 - journals.plos.org
The diversity of virus populations within single infected hosts presents a major difficulty for
the natural immune response as well as for vaccine design and antiviral drug therapy …

Expert consensus statement on the science of HIV in the context of criminal law

F Barré‐Sinoussi, SS Abdool Karim… - Journal of the …, 2018 - Wiley Online Library
Introduction Globally, prosecutions for non‐disclosure, exposure or transmission of HIV
frequently relate to sexual activity, biting, or spitting. This includes instances in which no …

Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients

C Song, Y Wang, W Li, B Hu, G Chen, P Xia, W Wang… - MedRxiv, 2020 - medrxiv.org
Abstract Background As of March 11, 2020, the COVID-19 outbreak was declared as a
pandemic. Expending our understanding of the transmission routes of the viral infection is …

[HTML][HTML] Network dynamics of eukaryotic LTR retroelements beyond phylogenetic trees

C Llorens, A Muñoz-Pomer, L Bernad, H Botella… - Biology direct, 2009 - Springer
Background Sequencing projects have allowed diverse retroviruses and LTR
retrotransposons from different eukaryotic organisms to be characterized. It is known that …

[HTML][HTML] Retroviral RNA dimerization: from structure to functions

N Dubois, R Marquet, JC Paillart… - Frontiers in …, 2018 - frontiersin.org
The genome of the retroviruses is a dimer composed by two homologous copies of genomic
RNA (gRNA) molecules of positive polarity. The dimerization process allows two gRNA …

[HTML][HTML] No coexistence for free: neutral null models for multistrain pathogens

M Lipsitch, C Colijn, T Cohen, WP Hanage, C Fraser - Epidemics, 2009 - Elsevier
In most pathogens, multiple strains are maintained within host populations. Quantifying the
mechanisms underlying strain coexistence would aid public health planning and improve …

A standardized framework for accurate, high-throughput genotyping of recombinant and non-recombinant viral sequences

LCJ Alcantara, S Cassol, P Libin… - Nucleic acids …, 2009 - academic.oup.com
Human immunodeficiency virus type-1 (HIV-1), hepatitis B and C and other rapidly evolving
viruses are characterized by extremely high levels of genetic diversity. To facilitate diagnosis …

A molecular clock for malaria parasites

RE Ricklefs, DC Outlaw - Science, 2010 - science.org
The evolutionary origins of new lineages of pathogens are fundamental to understanding
emerging diseases. Phylogenetic reconstruction based on DNA sequences has revealed …

The evolution of HIV: inferences using phylogenetics

E Castro-Nallar, M Pérez-Losada, GF Burton… - Molecular phylogenetics …, 2012 - Elsevier
Molecular phylogenetics has revolutionized the study of not only evolution but also disparate
fields such as genomics, bioinformatics, epidemiology, ecology, microbiology, molecular …