The HIV epidemic: high-income countries
SH Vermund, AJ Leigh-Brown - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The HIV epidemic in higher-income nations is driven by receptive anal intercourse, injection
drug use through needle/syringe sharing, and, less efficiently, vaginal intercourse. Alcohol …
drug use through needle/syringe sharing, and, less efficiently, vaginal intercourse. Alcohol …
Evolutionary mechanisms of persistence and diversification of a calicivirus within endemically infected natural host populations
KP Coyne, RM Gaskell, S Dawson, CJ Porter… - Journal of …, 2007 - Am Soc Microbiol
In order to understand the evolutionary mechanisms of persistence and diversification within
the Caliciviridae, we have been exploiting endemic infection of feline calicivirus within five …
the Caliciviridae, we have been exploiting endemic infection of feline calicivirus within five …
Virus maturation as a new HIV-1 therapeutic target
CS Adamson, K Salzwedel… - Expert opinion on …, 2009 - Taylor & Francis
Development of novel therapeutic targets against HIV-1 is a high research priority owing to
the serious clinical consequences associated with acquisition of resistance to current …
the serious clinical consequences associated with acquisition of resistance to current …
[PDF][PDF] HIV-1 infection, microenvironment and endothelial cell dysfunction
P Mazzuca, A Caruso, F Caccuri - New Microbiol, 2016 - newmicrobiologica.org
HIV-1 promotes a generalized immune activation that involves the main targets of HIV-1
infection but also cells that are not sensitive to viral infection. ECs display major dysfunctions …
infection but also cells that are not sensitive to viral infection. ECs display major dysfunctions …
[图书][B] Biological confinement of genetically engineered organisms
National Research Council, Division on Earth… - 2004 - books.google.com
Genetically engineered organisms (GEOs) have been under development for more than 20
years while GE crops have been grown commercially during the last decade. During this …
years while GE crops have been grown commercially during the last decade. During this …
A framework for evolutionary systems biology
L Loewe - BMC systems biology, 2009 - Springer
Background Many difficult problems in evolutionary genomics are related to mutations that
have weak effects on fitness, as the consequences of mutations with large effects are often …
have weak effects on fitness, as the consequences of mutations with large effects are often …
Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights
Preventing the spread of infectious diseases remains an urgent priority worldwide, and this
is driving the development of advanced nanotechnology to diagnose infections at the point …
is driving the development of advanced nanotechnology to diagnose infections at the point …
The role of HIV integration in viral persistence: no more whistling past the proviral graveyard
F Maldarelli - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
A substantial research effort has been directed to identifying strategies to eradicate or
control HIV infection without a requirement for combination antiretroviral therapy (cART). A …
control HIV infection without a requirement for combination antiretroviral therapy (cART). A …
A novel construction of genome space with biological geometry
A genome space is a moduli space of genomes. In this space, each point corresponds to a
genome. The natural distance between two points in the genome space reflects the …
genome. The natural distance between two points in the genome space reflects the …
Molecular footprint of drug-selective pressure in a human immunodeficiency virus transmission chain
Known human immunodeficiency virus (HIV) transmission histories are invaluable models
for investigating the evolutionary and transmission dynamics of the virus and to assess the …
for investigating the evolutionary and transmission dynamics of the virus and to assess the …