Purpose Spontaneous oocyte activation (SOA) is a recently classified phenomenon
characterized by the presence of a single pronucleus immediately following oocyte retrieval …

It is currently a challenge to perform noninvasive molecular biological analysis of in vitro
fertilized embryos. In this issue of Cell Genomics, Wu et al. 1 developed a non-invasive …

Human naive pluripotent stem cells have the remarkable ability to generate blastoids
comprising trophectoderm, epiblast, and hypoblast-like cells. In this issue, Taubenschmid …

Despite the wide use of ART over the past few decades, the efficiency in terms of
pregnancies and live birth rates (LBR) has reached a standstill (Eskew and Jungheim …

Background Mammalian gonadal sex is determined by the presence or absence of a Y
chromosome and the subsequent production of sex hormones contributes to secondary …

Expression of the embryonic poly (A)-binding protein (EPAB) in frog, mouse, and human
oocytes and early-stage embryos is maintained at high levels until embryonic genome …

In recent years, single-cell or low-input multi-omics techniques have brought a revolution in
the study of pre-implantation embryo development. However, single-cell or low-input …

 Abstract Patterns of meiotic chromosome segregation were analyzed in cleavage stage and
blastocyst stage human embryos from couples with autosomal reciprocal translocations …

Отличительной чертой раннего эмбрионального развития млекопитающих, особенно
человека, являются частые хромосомные аномалии. Анеуплоидии считаются …

Intrafamilial occurrence of cancer is a well-known hard aspect of life with psychological,
social, and financial aspects that members of the affected families must front. Familial …