There is an on-going demand in recent years for safer and “greener” hair coloring agents
with the global consumer awareness of the adverse effects of synthetic hair dyes. The belief …

In the global movement to find the appropriate agents to fight the coronavirus disease of
2019 (COVID-19), emetine is one of the strongest anti-SARS-CoV-2 compounds with sub …

Background Shikonin, a natural naphthoquinone compound, has a wide range of
pharmacological effects, but its anti-tumor effect and underlying mechanisms in bladder …

With the increasing concerns of food safety and public health, tremendous efforts have been
concentrated on the development of effective, reliable, nondestructive methods to evaluate …

Regulated cell death (RCD) refers to programmed cell death regulated by various protein
molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis …

The newly emerged coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) that caused the COVID-19 pandemic, is the closest relative of SARS-CoV with high …

P38 mitogen‐activated protein kinase (p38 MAPK) signaling pathway is closely related to
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …

Diabetes mellitus is known as one of the most life-threatening diseases and has attracted
the attention of medicinal chemists. The design and synthesis of novel potential candidates …

Chalcone is an interesting scaffold found in the structure of many naturally occurring
molecules. Medicinal chemists are commonly interested in designing new chalcone‐based …

Echium italicum L. is found to produce shikonin and its natural derivatives such as
acetylshikonin that has cytotoxic activity on cancer cells. Thus, in vitro mass production of …