Engineered EV-mimetic nanoparticles as therapeutic delivery vehicles for high-grade serous ovarian cancer

AA Al-Dossary, EA Tawfik, AC Isichei, X Sun, J Li… - Cancers, 2021 - mdpi.com
Simple Summary In this review, we begin with the role of natural extracellular vesicles (EVs)
in high-grade serous ovarian cancer (HGSOC). Then, we narrow our focus on the …

Targeted drug delivery in lipid-like nanocages and extracellular vesicles

AV Sokolov, NN Kostin, LA Ovchinnikova… - Acta Naturae …, 2019 - cyberleninka.ru
The possibility of targeted drug delivery to a specific tissue, organ, or cell has opened new
promising avenues in treatment development. The technology of targeted delivery aims to …

[HTML][HTML] Exosomes secreted under hypoxia enhance stemness in Ewing's sarcoma through miR-210 delivery

MJ Kling, NK Chaturvedi, V Kesherwani, DW Coulter… - Oncotarget, 2020 - ncbi.nlm.nih.gov
Intercellular communication between tumor cells within the hypoxic microenvironment
promote aggressiveness and poor patient prognoses for reasons that remain unclear. Here …

SARS-CoV-2 and extracellular vesicles: An intricate interplay in pathogenesis, diagnosis and treatment

C Sbarigia, D Vardanyan, L Buccini… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are widely recognized as intercellular communication mediators.
Among the different biological processes, EVs play a role in viral infections, supporting virus …

[HTML][HTML] Extracellular vesicles as novel drug delivery systems to target cancer and other diseases: Recent advancements and future perspectives

D Ramesh, S Bakkannavar, VR Bhat, K Sharan - F1000Research, 2023 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are lipid-bound vesicles produced into the extracellular space
by cells. Apoptotic bodies (ApoBD), microvesicles (MVs), and exosomes are examples of …

Matrix-Bound Nanovesicles: What Are They and What Do They Do?

LM Piening, RA Wachs - Cells Tissues Organs, 2023 - karger.com
Over the past 50 years, several different types of extracellular vesicles have been
discovered including exosomes, microvesicles, and matrix vesicles. These vesicles are …

Exosome-mediated repair of intervertebral disc degeneration: The potential role of miRNAs

HS Wang, S Lin, HM Yu - Current Stem Cell Research & …, 2024 - ingentaconnect.com
Intervertebral disc degeneration (IVDD) is a serious condition that manifests as low back
pain, intervertebral disc protrusion, and spinal canal stenosis. At present, the main treatment …

Exosome-Mediated Paracrine Signaling Unveils miR-1246 as a Driver of Aggressiveness in Fusion-Negative Rhabdomyosarcoma

F Ramadan, R Saab, F Ghamloush, R Khoueiry… - Cancers, 2024 - mdpi.com
Simple Summary Rhabdomyosarcoma (RMS) is a rare cancer that occurs in children and
adolescents. The presence of metastasis is associated with poor outcomes and highlights …

[HTML][HTML] Current advancement of exosomes as biomarkers for cancer diagnosis and forecasting

EA Bhat, N Sajjad, FM Thokar - Cancer Treatment and Research …, 2021 - Elsevier
Exosomes are normal vesicles produced in the late endosomes of a cell. They are secreted
by cells and play a role in cell-to-cell contact. They are an invaluable aid in cancer diagnosis …

[HTML][HTML] The Roles of Exosome-Derived microRNAs in Cardiac Fibrosis

X Tang, M Leng, W Tang, Z Cai, L Yang, L Wang… - Molecules, 2024 - mdpi.com
Cardiovascular disease (CVD) stands as the foremost cause of patient mortality, and the
lack of early diagnosis and defined treatment targets significantly contributes to the …