Improving biohydrogen productivity by microbial dark-and photo-fermentations: novel data and future approaches

K Trchounian, RG Sawers, A Trchounian - Renewable and Sustainable …, 2017 - Elsevier
Hydrogen (H 2) is an effective, environmentally friendly and renewable source of fuel that
can be produced during dark-and photo-fermentation by different facultative and obligate …

Anaerobic formate and hydrogen metabolism

C Pinske, RG Sawers - EcoSal Plus, 2016 - Am Soc Microbiol
Numerous recent developments in the biochemistry, molecular biology, and physiology of
formate and H2 metabolism and of the [NiFe]-hydrogenase (Hyd) cofactor biosynthetic …

[HTML][HTML] Structural basis for bacterial energy extraction from atmospheric hydrogen

R Grinter, A Kropp, H Venugopal, M Senger, J Badley… - Nature, 2023 - nature.com
Diverse aerobic bacteria use atmospheric H2 as an energy source for growth and survival.
This globally significant process regulates the composition of the atmosphere, enhances soil …

A soil actinobacterium scavenges atmospheric H2 using two membrane-associated, oxygen-dependent [NiFe] hydrogenases

C Greening, M Berney, K Hards… - Proceedings of the …, 2014 - National Acad Sciences
In the Earth's lower atmosphere, H2 is maintained at trace concentrations (0.53 ppmv/0.40
nM) and rapidly turned over (lifetime≤ 2.1 y− 1). It is thought that soil microbes, likely …

Novel, oxygen-insensitive group 5 [NiFe]-hydrogenase in Ralstonia eutropha

C Schäfer, B Friedrich, O Lenz - Applied and environmental …, 2013 - Am Soc Microbiol
Recently, a novel group of [NiFe]-hydrogenases has been defined that appear to have a
great impact in the global hydrogen cycle. This so-called group 5 [NiFe]-hydrogenase is …

Physiology and Bioenergetics of [NiFe]-Hydrogenase 2-Catalyzed H2-Consuming and H2-Producing Reactions in Escherichia coli

C Pinske, M Jaroschinsky, S Linek, CL Kelly… - Journal of …, 2015 - Am Soc Microbiol
Escherichia coli uptake hydrogenase 2 (Hyd-2) catalyzes the reversible oxidation of H2 to
protons and electrons. Hyd-2 synthesis is strongly upregulated during growth on glycerol or …

How a Formate Dehydrogenase Responds to Oxygen: Unexpected O2 Insensitivity of an Enzyme Harboring Tungstopterin, Selenocysteine, and [4Fe–4S] Clusters

JE Graham, D Niks, GM Zane, Q Gui, K Hom… - ACS …, 2022 - ACS Publications
The reversible two-electron interconversion of formate and CO2 is catalyzed by both
nonmetallo-and metallo-formate dehydrogenases (FDHs). The latter group comprises …

Mechanisms for hydrogen production by different bacteria during mixed-acid and photo-fermentation and perspectives of hydrogen production biotechnology

A Trchounian - Critical reviews in biotechnology, 2015 - Taylor & Francis
H2 has a great potential as an ecologically-clean, renewable and capable fuel. It can be
mainly produced via hydrogenases (Hyd) by different bacteria, especially Escherichia coli …

Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes

D Sychantha, X Chen, K Koteva, G Prehna… - Nature …, 2024 - nature.com
Microbial Ni2+ homeostasis underpins the virulence of several clinical pathogens. Ni2+ is
an essential cofactor in urease and [NiFe]-hydrogenases involved in colonization and …

Novel insights into the bioenergetics of mixed‐acid fermentation: can hydrogen and proton cycles combine to help maintain a proton motive force?

A Trchounian, R Gary Sawers - IUBMB life, 2014 - Wiley Online Library
Escherichia coli possesses four [NiFe]‐hydrogenases that catalyze the reversible redox
reaction of 2H++ 2e−↔ H2. These enzymes together have the potential to form a hydrogen …