Two decades ago, the sequence of the first human genome was published. Since then,
advances in genome technologies have resulted in whole-genome sequencing and …

Black men are disproportionately affected by prostate cancer (PCa), with earlier
presentation, more aggressive disease, and higher mortality rates versus White men …

BACKGROUND. Liquid biopsies have demonstrated that the constitutively active androgen
receptor splice variant-7 (AR-V7) associates with reduced response and overall survival …

Prostate cancer (PCa) is globally the second most diagnosed cancer type and the most
common cause of cancer-related deaths in men. Family history of PCa, hereditary breast …

Prostate cancer is the most prevalent non-skin cancer in men and is the leading cause of
cancer-related death. Early detection of prostate cancer is largely determined by a widely …

Simple Summary Prostate cancer is the most common malignancy in men, with a high
mortality rate when disease progresses to metastasis and therapeutic resistance. Evidence …

Multiple studies have confirmed that speckle-type pox virus and zinc finger (POZ) protein
(SPOP) functions as a substrate adaptor of cullin 3-based E3 ligase and has a crucial role in …

Abstract Context Prostate cancer (PCa) is a complex disease that disproportionately impacts
Black men in the USA. The structural factors that drive heterogeneous outcomes for patients …

Background: Nitrate and trihalomethanes (THMs) in drinking water are widespread and are
potential human carcinogens. Objective: We evaluated the association between drinking …

In the United States, prostate cancer (CaP) remains the second leading cause of cancer
deaths in men. CaP is predominantly indolent at diagnosis, with a small fraction (25–30%) …