Pyroptosis-related non-coding RNAs emerging players in atherosclerosis pathology

WMA Khojali, NE Khalifa, F Alshammari, S Afsar… - … -Research and Practice, 2024 - Elsevier
Globally, atherosclerosis a persistent inflammatory condition of the artery walls continues to
be the primary cause of cardiovascular illness and death. The ncRNAs are important …

Pyroptosis in Diabetic Peripheral Neuropathy and its Therapeutic Regulation

A Al Mamun, C Shao, P Geng, S Wang… - Journal of Inflammation …, 2024 - Taylor & Francis
Pyroptosis is a pro-inflammatory form of cell death resulting from the activation of
gasdermins (GSDMs) pore-forming proteins and the release of several pro-inflammatory …

Super enhancer-associated circRNA-circLrch3 regulates hypoxia-induced pulmonary arterial smooth muscle cells pyroptosis by formation of R-loop with host gene

H Liu, Y Jiang, R Shi, Y Hao, M Li, J Bai, H Wang… - International Journal of …, 2024 - Elsevier
Background Pulmonary hypertension (PH) is a complex vascular disorder, characterized by
pulmonary vessel remodeling and perivascular inflammation. Pulmonary arterial smooth …

[HTML][HTML] Oridonin exerts anticonvulsant profile and neuroprotective activity in epileptic mice by inhibiting NLRP3-mediated pyroptosis

T Zhao, X Zhang, X Cui, S Su, L Li, Y Chen… - International …, 2024 - Elsevier
Background Epilepsy is a chronic disabling disease poorly controlled by available
antiseizure medications. Oridonin, a bioactive alkaloid with anti-inflammatory properties and …

Homocysteine Facilitates the Formation of Carotid Atherosclerotic Plaque Through Inflammatory and Noninflammatory Mechanisms

Q Zhang, C Wu, X Tan, C Li, Y Liu… - Metabolic Syndrome and …, 2024 - liebertpub.com
Background: Elevated homocysteine (Hcy) was considered a significant risk factor in the
development and progression of carotid atherosclerosis (CAS), which involves a …