Omicron BA. 2 lineage, the “stealth” variant: is it truly a silent epidemic? A literature review

G Tiecco, S Storti, S Arsuffi, M Degli Antoni… - International Journal of …, 2022 - mdpi.com
The epidemic curve of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
silently rising again. Worldwide, the dominant SARS-CoV-2 variant of concern (VOC) is …

Blood transcriptomics analysis offers insights into variant-specific immune response to SARS-CoV-2

M Hoffmann, LL Willruth, A Dietrich, HK Lee, L Knabl… - Scientific Reports, 2024 - nature.com
Bulk RNA sequencing (RNA-seq) of blood is typically used for gene expression analysis in
biomedical research but is still rarely used in clinical practice. In this study, we propose that …

Three in one: An effective and universal vaccine expressing heterologous tandem RBD trimer by rabies virus vector protects mice against SARS-CoV-2

J Huang, W Wang, H Li, Y Bai, Y Song, C Jiao, H Jin… - Antiviral Research, 2024 - Elsevier
The rapid emergence of Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-
CoV-2) variants, coupled with severe immune evasion and imprinting, has jeopardized the …

Deciphering the molecular nexus between Omicron infection and acute kidney injury: a bioinformatics approach

L Wang, A Chen, L Zhang, J Zhang, S Wei… - Frontiers in Molecular …, 2024 - frontiersin.org
Background The ongoing global health crisis of COVID-19, and particularly the challenges
posed by recurrent infections of the Omicron variant, have significantly strained healthcare …

[HTML][HTML] Variant-and vaccination-specific alternative splicing profiles in SARS-CoV-2 infections

SG Lee, PA Furth, L Hennighausen, HK Lee - Iscience, 2024 - cell.com
The COVID-19 pandemic, driven by the SARS-CoV-2 virus and its variants, highlights the
important role of understanding host-viral molecular interactions influencing infection …

Type I Interferon Pathway-Related Hub Genes as a Potential Therapeutic Target for SARS-CoV-2 Omicron Variant-Induced Symptoms

Z Lin, M Xue, Z Wu, Z Liu, Q Yang, J Hu, J Peng, L Yu… - Microorganisms, 2023 - mdpi.com
Background: The global pandemic of COVID-19 is caused by the rapidly evolving severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical presentation of SARS …

[HTML][HTML] Omicron's intrinsic gene-gene interactions jumped away from earlier SARS-CoV-2 variants and gene homologs between humans and animals

Z Zhang - Advances in Biomarker Sciences and Technology, 2023 - Elsevier
Background Omicron and its subvariants have become the predominant SARS-CoV-2
variants worldwide. The Omicron's basic reproduction number (R0) has been close to 20 or …