Antimicrobial peptide action on parasites

M Torrent, D Pulido, L Rivas, D Andreu - Current drug targets, 2012 - ingentaconnect.com
Diseases caused by protozoan parasites can pose a severe thread to human health and are
behind some serious neglected tropical diseases like malaria and leishmaniasis. Though …

Single and mixed-species trypanosome and microsporidia infections elicit distinct, ephemeral cellular and humoral immune responses in honey bees

RS Schwarz, JD Evans - Developmental & Comparative Immunology, 2013 - Elsevier
Frequently encountered parasite species impart strong selective pressures on host immune
system evolution and are more apt to concurrently infect the same host, yet molecular …

Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II

P Schmitt, M Wilmes, M Pugnière, A Aumelas… - Journal of Biological …, 2010 - ASBMB
Three oyster defensin variants (Cg-Defh1, Cg-Defh2, and Cg-Defm) were produced as
recombinant peptides and characterized in terms of activities and mechanism of action. In …

The midgut microbiota plays an essential role in sand fly vector competence for Leishmania major

I Louradour, CC Monteiro, E Inbar, K Ghosh… - Cellular …, 2017 - Wiley Online Library
For many arthropod vectors, the diverse bacteria and fungi that inhabit the gut can
negatively impact pathogen colonization. Our attempts to exploit antibiotic treatment of …

[HTML][HTML] Cysteine-stabilized αβ defensins: from a common fold to antibacterial activity

R de Oliveira Dias, OL Franco - Peptides, 2015 - Elsevier
Antimicrobial peptides (AMPs) seem to be promising alternatives to common antibiotics,
which are facing increasing bacterial resistance. Among them are the cysteine-stabilized αβ …

Innate immune responses of a scleractinian coral to vibriosis

J Vidal-Dupiol, O Ladrière… - Journal of Biological …, 2011 - ASBMB
Scleractinian corals are the most basal eumetazoan taxon and provide the biological and
physical framework for coral reefs, which are among the most diverse of all ecosystems …

Effects of host species on microbiota composition in Phlebotomus and Lutzomyia sand flies

A Tabbabi, D Mizushima, DS Yamamoto, H Kato - Parasites & vectors, 2023 - Springer
Background Blood-sucking phlebotomine sand flies are vectors of the protozoan parasites
Leishmania spp. Although the intestinal microbiota is involved in a wide range of biological …

The medical potential of antimicrobial peptides from insects

M Tonk, A Vilcinskas - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
Antimicrobial peptides (AMPs) are peptide-based effector molecules produced by the innate
immune system to combat microbes. Insects produce the broadest repertoire of AMPs, and …

Molecular characterization of two isoforms of defensin from hemocytes of the oyster Crassostrea gigas

M Gonzalez, Y Gueguen, G Desserre… - Developmental & …, 2007 - Elsevier
Antimicrobial peptides (AMPs) are important components of the host innate immune
response against microbial invasion. We previously characterized the first AMP from an …

[HTML][HTML] A lipophosphoglycan-independent development of Leishmania in permissive sand flies

J Myskova, M Svobodova, SM Beverley, P Volf - Microbes and infection, 2007 - Elsevier
Leishmaniases are serious parasitic diseases the etiological organisms of which are
transmitted by insect vectors, phlebotominae sand flies. Two sand fly species, Phlebotomus …