Antiparasitic peptides

J Pretzel, F Mohring, S Rahlfs, K Becker - Yellow Biotechnology I: Insect …, 2013 - Springer
<? xm-replace_text {Heading}?> Abstract The most important parasitic diseases, malaria,
leishmaniasis, trypanosomiasis, and schistosomiasis, are a great burden to mankind …

Phlebotomus papatasi Antimicrobial Peptides in Larvae and Females and a Gut-Specific Defensin Upregulated by Leishmania major Infection

B Kykalová, L Tichá, P Volf, E Loza Telleria - Microorganisms, 2021 - mdpi.com
Phlebotomus papatasi is the vector of Leishmania major, causing cutaneous leishmaniasis
in the Old World. We investigated whether P. papatasi immunity genes were expressed …

[HTML][HTML] Evidence of a conserved mammalian immunosuppression mechanism in Lutzomyia longipalpis upon infection with Leishmania

EL Telleria, B Tinoco-Nunes, DM Forrest… - Frontiers in …, 2023 - frontiersin.org
Introduction Sand flies (Diptera: Phlebotominae) belonging to the Lutzomyia genus transmit
Leishmania infantum parasites. To understand the complex interaction between the vector …

Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major-infected …

M Ramalho-Ortigão, RC Jochim, JM Anderson… - BMC genomics, 2007 - Springer
Background In sandflies, the blood meal is responsible for the induction of several
physiologic processes that culminate in egg development and maturation. During blood …

Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with …

D da Silva Gonçalves, I Iturbe-Ormaetxe… - Parasites & vectors, 2019 - Springer
Background The leishmaniases are important neglected diseases caused by Leishmania
spp. which are transmitted by sand flies, Lutzomyia longipalpis being the main vector of …

Use of peptide libraries for identification and optimization of novel antimicrobial peptides

M Ashby, A Petkova, J Gani, R Mikut… - Current Topics in …, 2017 - ingentaconnect.com
The increasing rates of resistance among bacteria and to a lesser extent fungi have resulted
in an urgent need to find new molecules that hold therapeutic promise against multidrug …

Infection with the trypanosome Crithidia bombi and expression of immune-related genes in the bumblebee Bombus terrestris

H Schlüns, BM Sadd, P Schmid-Hempel… - Developmental & …, 2010 - Elsevier
Social bees and other insects are frequently parasitized by a large range of different
microorganisms. Among these is Crithidia bombi (Kinetoplastida: Trypanosomatidae), a …

Theta‐Defensins to Counter COVID‐19 as Furin Inhibitors: In Silico Efficiency Prediction and Novel Compound Design

M Negahdaripour, MR Rahbar… - … Methods in Medicine, 2022 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2), was characterized as a pandemic by the World Health …

[HTML][HTML] Analysis of ESTs from Lutzomyia longipalpis sand flies and their contribution toward understanding the insect–parasite relationship

RJ Dillon, AC Ivens, C Churcher, N Holroyd, MA Quail… - Genomics, 2006 - Elsevier
An expressed sequence tag library has been generated from a sand fly vector of visceral
leishmaniasis, Lutzomyia longipalpis. A normalized cDNA library was constructed from …

Differential expression of immune defences is associated with specific host-parasite interactions in insects

C Riddell, S Adams, P Schmid-Hempel, EB Mallon - PLoS One, 2009 - journals.plos.org
Recent ecological studies in invertebrates show that the outcome of an infection is
dependent on the specific pairing of host and parasite. Such specificity contrasts the long …