[HTML][HTML] Blood-brain barrier dysfunction amplifies the development of neuroinflammation: understanding of cellular events in brain microvascular endothelial cells for …
F Takata, S Nakagawa, J Matsumoto… - Frontiers in cellular …, 2021 - frontiersin.org
Neuroinflammation is involved in the onset or progression of various neurodegenerative
diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
[HTML][HTML] Blood–brain barrier dysfunction in mild traumatic brain injury: evidence from preclinical murine models
Mild traumatic brain injury (mTBI) represents more than 80% of total TBI cases and is a
robust environmental risk factor for neurodegenerative diseases including Alzheimer's …
robust environmental risk factor for neurodegenerative diseases including Alzheimer's …
[HTML][HTML] Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
C Greene, R Connolly, D Brennan, A Laffan… - Nature …, 2024 - nature.com
Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19)
pathogenesis and may predispose to the neurological sequelae associated with long …
pathogenesis and may predispose to the neurological sequelae associated with long …
Validation and comparison of instrumented mouthguards for measuring head kinematics and assessing brain deformation in football impacts
Because of the rigid coupling between the upper dentition and the skull, instrumented
mouthguards have been shown to be a viable way of measuring head impact kinematics for …
mouthguards have been shown to be a viable way of measuring head impact kinematics for …
Memantine inhibits cortical spreading depolarization and improves neurovascular function following repetitive traumatic brain injury
MA MacLean, JH Muradov, R Greene… - Science …, 2023 - science.org
Cortical spreading depolarization (CSD) is a promising target for neuroprotective therapy in
traumatic brain injury (TBI). We explored the effect of NMDA receptor antagonism on …
traumatic brain injury (TBI). We explored the effect of NMDA receptor antagonism on …
The known unknowns: an overview of the state of blood-based protein biomarkers of mild traumatic brain injury
Blood-based protein biomarkers have revolutionized several fields of medicine by enabling
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …
Identifying Factors Associated with Head Impact Kinematics and Brain Strain in High School American Football via Instrumented Mouthguards
Repeated head impact exposure and concussions are common in American football.
Identifying the factors associated with high magnitude impacts aids in informing sport policy …
Identifying the factors associated with high magnitude impacts aids in informing sport policy …
Rapid estimation of entire brain strain using deep learning models
Objective: Many recent studies suggest that brain deformation resulting from head impacts
are linked to the corresponding clinical outcome, such as mild traumatic brain injury (mTBI) …
are linked to the corresponding clinical outcome, such as mild traumatic brain injury (mTBI) …
Neuroinflammatory responses of microglia in central nervous system trauma
DC Shields, A Haque, NL Banik - Journal of Cerebral Blood …, 2020 - journals.sagepub.com
Although relatively few in number compared to astrocytes and neurons, microglia
demonstrate multiple, varied neuroimmunological functions in the central nervous system …
demonstrate multiple, varied neuroimmunological functions in the central nervous system …
[HTML][HTML] Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective
The blood-brain barrier (BBB) consists of specialized cells that tightly regulate the in-and
outflow of molecules from the blood to brain parenchyma, protecting the brain's …
outflow of molecules from the blood to brain parenchyma, protecting the brain's …