Mechanisms of action of glucagon-like peptide 1 in the pancreas

ME Doyle, JM Egan - Pharmacology & therapeutics, 2007 - Elsevier
Glucagon-like peptide 1 (GLP-1) is a hormone that is encoded in the proglucagon gene. It is
mainly produced in enteroendocrine L cells of the gut and is secreted into the blood stream …

Regulation of vascular reactivity by established and emerging GPCRs

JJ Maguire, AP Davenport - Trends in pharmacological sciences, 2005 - cell.com
The vascular system is rich in G-protein-coupled receptors (GPCRs), particularly Class 1
GPCRs, which are activated by an eclectic range of chemical entities including peptides …

Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

S Roy-Carson, K Natukunda, H Chou, N Pal, C Farris… - BMC genomics, 2017 - Springer
Background Motility and the coordination of moving food through the gastrointestinal tract
rely on a complex network of neurons known as the enteric nervous system (ENS). Despite …

Substance P-and choline acetyltransferase immunoreactivities in somatostatin-containing, human submucosal neurons

J Beyer, S Jabari, TT Rau, W Neuhuber… - Histochemistry and cell …, 2013 - Springer
The submucous layers of human small and large intestines contain at least two separate
neuron populations. Besides morphological features, they differ in their immunoreactivities …

Omeprazole-induced slowing of gastrointestinal transit in mice can be countered with tegaserod

A Cowan, DL Earnest, G Ligozio, MA Rojavin - European journal of …, 2005 - Elsevier
Omeprazole, besides suppressing gastric acid, causes delayed gastric emptying, which may
be associated with aggravated dyspeptic symptoms. Effects of omeprazole on small …

Intestinal immunomodulation. Role of regulative peptides and promising pharmacological activities

V Motilva, E Talero, JR Calvo, I Villegas… - Current …, 2008 - ingentaconnect.com
About 50 peptides, and a similar number of peptide receptors, are known to be present in
the gut and this amount is likely to rise significantly over the next few years. While there has …

Peptide and protein delivery through carrageenan, alginic acid, agar, and myrrh

PM Raj, A Gupta, KK Sahu, G Kumar, S Minz… - Peptide and Protein Drug …, 2024 - Elsevier
Proteins and peptides play a vital role in normal cell functioning and maintaining human
physiology. Nowadays, many protein therapeutics have been discovered through the …

Proteins and peptides: The need to improve them as promising therapeutics for ulcerative colitis

KK Sahu, S Minz, M Kaurav… - … cells, nanomedicine, and …, 2016 - Taylor & Francis
The present review briefly describes the nature, type and pathogenesis of ulcerative colitis,
and explores the potential use of peptides and proteins in the treatment of inflammatory …

A 型肉毒毒素对内脏性疼痛镇痛作用的实验研究

李莉, 刘庆森, 杨云生 - 医学研究生学报, 2009 - cqvip.com
目的: 近年来A 型肉毒毒素(BTX-A) 在疼痛治疗中的作用已成为新的热点, 文中研究腹腔注射BTX-
A 在大鼠内脏性疼痛中的镇痛作用, 以及对肠壁乙酰胆碱酯酶(AChE), P 物质(SP) 表达的影响 …

[PDF][PDF] Immunhistochemische und morphologische Klassifizierung submuköser Neuronen im menschlichen Darm

J Breunig - 2023 - opus4.kobv.de
Zusammenfassung Hintergrund und Ziele Das Enterische Nervensystem (ENS) des
Menschen setzt sich aus mehreren ganglionären Nervengeflechten, dem Plexus …