Snake venoms are complex mixtures containing many different biologically active proteins
and peptides. A number of these proteins interact with components of the human hemostatic …

A. MAP Kinases Are Critical for Angiogenesis B. Integrins and Other MAPKs During
Angiogenesis IV. Alterations in Integrin–ECM Interactions During Angiogenesis A. The ECM …

The blockade of platelet integrin glycoprotein (GP) IIb/IIIa is a promising new antiplatelet
strategy. The binding of ligands or of the ligand-mimetic peptide RGD causes a …

Echistatin is a viper venom disintegrin containing RGD loop maintained by disulfide bridges.
It binds with a high affinity to αvβ3 and αIIbβ3 and it induces extensive conformational …

Angiogenesis refers to the process of remodeling the vascular tissue characterized by the
branching out of a new blood vessel from a pre‐existing vessel. Angiogenesis is particularly …

Snake venom proteins are broadly investigated in the different areas of life science. Direct
interaction of these compounds with cells may involve a variety of mechanisms that result in …

The integrin α9β1 is a multifunctional receptor that interacts with a variety of ligands
including vascular cell adhesion molecule 1, tenascin C and osteopontin. We found that this …

We have isolated and characterized EMS16, a potent and selective inhibitor of the α2β1
integrin, from Echis multisquamatus venom. It belongs to the family of C-lectin type of …

Viperistatin and VP12 isolated from Vipera paleastinae venom showed a potent inhibitory
activity against collagen receptors, α1β1 and α2β1 integrins, respectively. Structurally …

Repopulation of decellularized lung scaffolds (DLS) is limited due to alterations in the
repertoire and ratios of the residual extracellular matrix (ECM) proteins, characterized by eg …