SUMMARY ANSWER: Pregnant women with hereditary thrombophilia have an increased
risk of RPL, especially for pregnant women with the G1691A mutation of the factor V Leiden …

Growing evidence suggests that thrombophilia is associated with venous thromboembolism
(VTE) and adverse pregnancy outcomes. However, methodological limitations have made it …

В доступной форме в книге изложены основные события, произошедшие в
медицинской генетике и в молекулярной медицине после расшифровки генома …

Background Our aim was to assess the strength of the controversial association between
thrombophilia and fetal loss, and to examine whether it varies according to the timing or …

Recurrent miscarriage is a common pathology fond in 1% to 5% of reproductively active
couples. This chapter discusses the possible causes of recurrent miscarriage, and …

The influence of folate nutritional status on various pregnancy outcomes has long been
recognized. Studies conducted in the 1950s and 1960s led to the recognition of prenatal …

Miscarriage is one of the most frequent problems in human pregnancy. The most widely
accepted definition is that proposed by the World Health Organization (WHO) in 1977. The …

Recurrent spontaneous abortion (RSA) is defined as three or more consecutive pregnancy
losses prior to the 20th week of gestation. The etiology of recurrent spontaneous abortion is …

Background Recurrent pregnancy loss (RPL) is a significant clinical problem. Recently,
thrombophilias have been implicated as a possible cause. Factor V Leiden (FVL) and …

Pregnancy is hypercoagulable state. The field of thrombophilia; the tendency to thrombosis,
has been developed rapidly and has been linked to many aspects of pregnancy. It is …