Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of …

T Ishii, H Furuoka, M Kaya, T Kuhara - Biomedicines, 2021 - mdpi.com
We previously reported that 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced
Parkinson's disease (PD) model mice (PD mice) facilitate hippocampal memory extinction …

[HTML][HTML] Agathobaculum butyriciproducens shows neuroprotective effects in a 6-OHDA-induced mouse model of Parkinson's disease

YK Ryu, DH Chang, HY Park, J Go… - … of Microbiology and …, 2022 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is the second-most prevalent neurodegenerative disease and is
characterized by dopaminergic neuronal death in the midbrain. Recently, the association …

Bacterial Lysate from the Multi-Strain Probiotic SLAB51 Triggers Adaptative Responses to Hypoxia in Human Caco-2 Intestinal Epithelial Cells under Normoxic …

F Lombardi, FR Augello, P Palumbo, L Bonfili… - International Journal of …, 2023 - mdpi.com
Hypoxia-inducible factor-1α (HIF-1α), a central player in maintaining gut-microbiota
homeostasis, plays a pivotal role in inducing adaptive mechanisms to hypoxia and is …

SLAB51 multi-strain probiotic formula increases oxygenation in oxygen-treated preterm infants

ME Baldassarre, M Marazzato, M Pensa, MT Loverro… - Nutrients, 2023 - mdpi.com
Preterm infants are at risk of hypoxia and hyperoxia because of the immaturity of their
respiratory and antioxidant systems, linked to increased morbidity and mortality. This study …

Intestinal microflora changes in patients with mild alzheimer's disease in a Chinese cohort

Y Wang, L Li, X Zhao, S Sui, Q Wang… - Journal of …, 2022 - content.iospress.com
Background: Understanding the relationship between Alzheimer's disease (AD) and
intestinal flora is still a major scientific topic that continues to advance. Objective: To …

Evaluating the effectiveness of probiotics in relieving constipation in Parkinson's disease: A systematic review and meta-analysis

N Ghalandari, F Assarzadegan, H Mahdavi, E Jamshidi… - Heliyon, 2023 - cell.com
Objectives The aim of this study was to evaluate the effects of probiotics on the treatment of
constipation in patients with Parkinson's disease (PD) by analyzing data from published …

Tonic activation of NR2D-containing NMDARs exacerbates dopaminergic neuronal loss in MPTP-injected Parkinsonian mice

R Sharma, C Neupane, TL Pham, M Lee… - Journal of …, 2023 - Soc Neuroscience
NR2D subunit-containing NMDA receptors (NMDARs) gradually disappear during brain
maturation but can be recruited by pathophysiological stimuli in the adult brain. Here, we …

Microbiota-targeted therapies in inflammation resolution

F Strati, G Lattanzi, C Amoroso, F Facciotti - Seminars in Immunology, 2022 - Elsevier
Gut microbiota has been shown to systemically shape the immunological landscape,
modulate homeostasis and play a role in both health and disease. Dysbiosis of gut …

Neuroprotective potential of choline alfoscerate against β‐amyloid injury: Involvement of neurotrophic signals

M Catanesi, M d'Angelo, A Antonosante… - Cell biology …, 2020 - Wiley Online Library
Alzheimer's disease represents the most prevalent neurodegeneration worldwide, clinically
characterized by cognitive and memory impairment. New therapeutic approaches are …

The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota-liver-brain axis

C Giommi, M Lombó, HR Habibi, G Rossi… - Science of the Total …, 2024 - Elsevier
A plethora of studies have so far described the toxic effects of bisphenol A (BPA) on
organism health, highlighting the urgent need to find new strategies not only to reduce the …