Inflammaging and fatty acid oxidation in monocytes and macrophages

V Kruglov, IH Jang, CD Camell - Immunometabolism, 2024 - journals.lww.com
Fatty acid oxidation (FAO), primarily known as β-oxidation, plays a crucial role in breaking
down fatty acids within mitochondria and peroxisomes to produce cellular energy and …

Heterotopic mineralization (ossification or calcification) in aged musculoskeletal soft tissues: A new candidate marker for aging

GC Dai, H Wang, PP Lu, YJ Li, YC Gao, L Shi… - Ageing Research …, 2024 - Elsevier
Aging can lead to various disorders in organisms and with the escalating impact of
population aging, the incidence of age-related diseases is steadily increasing. As a major …

U-shaped association of systemic immune-inflammation index levels with cancer-related and all-cause mortality in middle-aged and older individuals with frailty

Z Zheng, H Luo, Q Xue - Archives of Gerontology and Geriatrics, 2024 - Elsevier
Purpose Frailty is a state of heightened vulnerability to stress, whether from within the body
or external factors. We aim to assess the prognostic value of the Systemic Immune …

The impact of ageing mechanisms on musculoskeletal system diseases in the elderly

Y Cai, Z Han, H Cheng, H Li, K Wang, J Chen… - Frontiers in …, 2024 - frontiersin.org
Ageing is an inevitable process that affects various tissues and organs of the human body,
leading to a series of physiological and pathological changes. Mechanisms such as …

Prevention, Assessment, and Management of Malnutrition in Older Adults with Early Stages of Cognitive Disorders

I Loda, E D'Angelo, E Marzetti, H Kerminen - Nutrients, 2024 - mdpi.com
Malnutrition is common in older adults, and its risk is greater in those living with dementia.
Relative to cognitively healthy peers, the prevalence of malnutrition is also increased in …

New Possibilities for Evaluating the Development of Age-Related Pathologies Using the Dynamical Network Biomarkers Theory

K Akagi, K Koizumi, M Kadowaki, I Kitajima, S Saito - Cells, 2023 - mdpi.com
Aging is the slowest process in a living organism. During this process, mortality rate
increases exponentially due to the accumulation of damage at the cellular level. Cellular …

Accelerated biological aging as potential mediator mediates the relationship between pro-inflammatory diets and the risk of depression and anxiety: A prospective …

F Lin, X Chen, Y Cai, Y Shi, Y Wang, Y Zeng… - Journal of Affective …, 2024 - Elsevier
Background The relationship between inflammatory dietary patterns and the risk of
depression/anxiety has not been clearly established due to differences in study populations …

The Molecular Mechanisms in Senescent Cells Induced by Natural Aging and Ionizing Radiation

M Ibragimova, A Kussainova, A Aripova, R Bersimbaev… - Cells, 2024 - mdpi.com
This review discusses the relationship between cellular senescence and radiation exposure.
Given the wide range of ionizing radiation sources encountered by people in professional …

Impact of social distancing from the COVID-19 pandemic on the immuno-inflammatory response of older adults

GB Nery, CAR de Araujo, GB da Silva, H Bittar… - BMC geriatrics, 2024 - Springer
Background Older adults, as the population considered at increased risk for severe COVID-
19, were the most impacted by social isolation. Thus, this study aimed to assess the salivary …

Insights into targeting cellular senescence with senolytic therapy: the journey from preclinical trials to clinical practice

P Chen, Y Wang, B Zhou - Mechanisms of Ageing and Development, 2024 - Elsevier
Interconnected, fundamental aging processes are central to many illnesses and diseases.
Cellular senescence is a mechanism that halts the cell cycle in response to harmful stimuli …