Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

Objective: The first 70 years of critical care can be considered a period of “industrial
revolution-like” advancement in terms of progressing the understanding and care of critical …

The agricultural ecosystem creates a platform for the development and dissemination of
antimicrobial resistance, which is promoted by the indiscriminate use of antibiotics in the …

Abstract Development of antibiotic resistance in bacteria is one of the major issues in the
present world and one of the greatest threats faced by mankind. Resistance is spread …

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Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …

Acinetobacter baumannii (named in honor of the American bacteriologists Paul and Linda
Baumann) is a Gram-negative, multidrug-resistant (MDR) pathogen that causes nosocomial …

The burden of multidrug resistance in Gram-negative bacilli (GNB) now represents a daily
issue for the management of antimicrobial therapy in intensive care unit (ICU) patients. In …

The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

The accuracy of the signs and tests that clinicians use to diagnose ventilator-associated
pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We …