The first steps towards the era of personalised vaccinology: predicting adverse reactions

P Pellegrino, FS Falvella, V Perrone… - The …, 2015 - nature.com
Until now, the occurrence of adverse reactions among individuals inoculated with identical
vaccines has been ascribed to unpredictable stochastic processes. Recent advances in …

New wisdom to defy an old enemy: summary from a scientific symposium at the 4th Influenza Vaccines for the World (IVW) 2012 Congress, 11 October, Valencia …

GA Poland, DM Fleming, JJ Treanor, E Maraskovsky… - Vaccine, 2013 - Elsevier
Both seasonal and pandemic influenza cause considerable morbidity and mortality globally.
In addition, the ongoing threat of new, unpredictable influenza pandemics from emerging …

Ontology-based precision vaccinology for deep mechanism understanding and precision vaccine development

J Xie, W Zi, Z Li, Y He - Current Pharmaceutical Design, 2021 - ingentaconnect.com
Vaccination is one of the most important innovations in human history. It has also become a
hot research area in a new application-the development of new vaccines against non …

Deep sequencing in pre-and clinical vaccine research

P Prachi, C Donati, F Masciopinto, R Rappuoli… - Public Health …, 2013 - karger.com
Vaccine research has experienced a quantum leap after the beginning of the genomics era.
High-throughput sequencing techniques, unlimited computing resources, as well as new …

Addressing viral resistance through vaccines

C Laughlin, A Schleif, CA Heilman - Future virology, 2015 - Taylor & Francis
Antimicrobial resistance is a serious healthcare concern affecting millions of people around
the world. Antiviral resistance has been viewed as a lesser threat than antibiotic resistance …

The role of Toll-like receptor 4 polymorphisms in vaccine immune response

P Pellegrino, FS Falvella, S Cheli, C Perrotta… - The …, 2016 - nature.com
Toll-like receptors (TLRs) are a class of pattern recognition receptors that are deputed to
recognise a range of molecular structures in pathogens. One of the most studied members of …

The composition of immune cells serves as a predictor of adaptive immunity in a cohort of 50‐to 74‐year‐old adults

RB Kennedy, WL Simon, MJ Gibson, KM Goergen… - …, 2016 - Wiley Online Library
Influenza causes significant morbidity and mortality annually. Although vaccination offers a
considerable amount of protection, it is far from perfect, especially in aging populations. This …

[PDF][PDF] Viral epidemics and vaccine preparedness

A Nandy, SC Basak - J Mol Pathol Epidemiol, 2017 - researchgate.net
Viral epidemics are occurring with increasing frequency raising concerns on public health
and preventive and therapeutic preparedness. At the turn of the new century it was the 2002 …

Systems approaches to computational modeling of the oral microbiome

DV Dimitrov - Frontiers in physiology, 2013 - frontiersin.org
Current microbiome research has generated tremendous amounts of data providing
snapshots of molecular activity in a variety of organisms, environments, and cell types …

New computational approach for peptide vaccine design against SARS-COV-2

S Biswas, S Manna, A Nandy, SC Basak - International Journal of Peptide …, 2021 - Springer
The design for vaccines using in silico analysis of genomic data of different viruses has
taken many different paths, but lack of any precise computational approach has constrained …