[HTML][HTML] Advances in the relationship between coronavirus infection and cardiovascular diseases

M Zhao, M Wang, J Zhang, J Ye, Y Xu, Z Wang… - Biomedicine & …, 2020 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19) has once again aroused people's
concern about coronavirus. Seven human coronaviruses (HCoVs) have been discovered so …

Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis

JL Nieto-Torres, ML DeDiego… - PLoS …, 2014 - journals.plos.org
Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E)
gene attenuates the virus. E gene encodes a small multifunctional protein that possesses …

Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival

ML DeDiego, JL Nieto-Torres, JA Regla-Nava… - Journal of …, 2014 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of a
respiratory disease that has a 10% mortality rate. We previously showed that SARS-CoV …

COVID-19 and cardiovascular disease: manifestations, pathophysiology, vaccination, and long-term implication

A Abdel Moneim, MA Radwan… - Current Medical Research …, 2022 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic is caused by a new
coronavirus family member, severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis

JM Jimenez-Guardeño, JL Nieto-Torres… - PLoS …, 2014 - journals.plos.org
A recombinant severe acute respiratory syndrome coronavirus (SARS-CoV) lacking the
envelope (E) protein is attenuated in vivo. Here we report that E protein PDZ-binding motif …

Pulmonary pathology of early‐phase COVID‐19 pneumonia in a patient with a benign lung lesion

Z Zeng, L Xu, XY Xie, HL Yan, BJ Xie, WZ Xu… - …, 2020 - Wiley Online Library
Aims An ongoing outbreak of 2019 novel coronavirus (CoV) disease (COVID‐19), caused by
severe acute respiratory syndrome (SARS) CoV‐2, has been spreading in multiple …

The envelope protein of SARS‐CoV‐2 increases intra‐Golgi pH and forms a cation channel that is regulated by pH

D Cabrera‐Garcia, R Bekdash… - The Journal of …, 2021 - Wiley Online Library
Key points We report a novel method for the transient expression of SARS‐CoV‐2 envelope
(E) protein in intracellular organelles and the plasma membrane of mammalian cells and …

Identification of the mechanisms causing reversion to virulence in an attenuated SARS-CoV for the design of a genetically stable vaccine

JM Jimenez-Guardeño, JA Regla-Nava… - PLoS …, 2015 - journals.plos.org
A SARS-CoV lacking the full-length E gene (SARS-CoV-∆ E) was attenuated and an
effective vaccine. Here, we show that this mutant virus regained fitness after serial passages …

Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair

K Martinez Lagunas, DP Savcigil, M Zrilic… - Science …, 2023 - science.org
Cell death coordinates repair programs following pathogen attack and tissue injury.
However, aberrant cell death can interfere with such programs and cause organ failure …

Beneficial effect of statins in COVID-19–related outcomes—brief report: a national population-based cohort study

HY Lee, J Ahn, J Park, C Kyung Kang… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Although statins are widely prescribed lipid-lowering drugs, there are concerns
about the safety of their use in the context of coronavirus disease 2019 (COVID-19), since …