[HTML][HTML] Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

[HTML][HTML] Autism spectrum disorder: focus on glutamatergic neurotransmission

M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

[HTML][HTML] Early-life differences in the gut microbiota composition and functionality of infants at elevated likelihood of developing autism spectrum disorder

S Zuffa, P Schimmel, A Gonzalez-Santana… - Translational …, 2023 - nature.com
Evidence from cross-sectional human studies, and preliminary microbial-based intervention
studies, have implicated the microbiota-gut-brain axis in the neurobiology of autism …

[HTML][HTML] GABA release from astrocytes in health and disease

W Kilb, S Kirischuk - International Journal of Molecular Sciences, 2022 - mdpi.com
Astrocytes are the most abundant glial cells in the central nervous system (CNS) mediating a
variety of homeostatic functions, such as spatial K+ buffering or neurotransmitter reuptake. In …

[HTML][HTML] Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

S Nisar, M Haris - Molecular psychiatry, 2023 - nature.com
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …

[HTML][HTML] Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL

S Liu, X Men, Y Guo, W Cai, R Wu, R Gao, W Zhong… - Microbiome, 2023 - Springer
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is a cerebral small vessel disease that carries mutations in …

[HTML][HTML] Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview

N Lampiasi, R Bonaventura, I Deidda, F Zito… - International Journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous collection of neurodevelopmental
disorders, difficult to diagnose and currently lacking treatment options. The possibility of …

[HTML][HTML] Prenatal exposure to benzodiazepines and Z-drugs in humans and risk of adverse neurodevelopmental outcomes in offspring: A systematic review

X Wang, T Zhang, I Ekheden, Z Chang… - Neuroscience & …, 2022 - Elsevier
When used during pregnancy, benzodiazepines (BZDs) and related z-drugs could pass
readily through the placenta and the foetal blood-brain barrier, where they can bind to γ …

[HTML][HTML] Three decades of valproate: a current model for studying autism Spectrum disorder

D Zarate-Lopez, AL Torres-Chávez… - Current …, 2023 - ncbi.nlm.nih.gov
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

Development of highly sensitive, flexible dual L-glutamate and GABA microsensors for in vivo brain sensing

SS Chu, HA Nguyen, D Lin, M Bhatti… - Biosensors and …, 2023 - Elsevier
Real-time tracking of neurotransmitter levels in vivo has been technically challenging due to
the low spatiotemporal resolution of current methods. Since the imbalance of cortical …