Dementia is a syndrome of global and progressive deterioration of cognitive skills,
especially memory, learning, abstract thinking, and orientation, usually affecting the elderly …

Translocase of outer mitochondrial membrane 40 (TOMM40) is located in the outer
membrane of mitochondria. TOMM40 is essential for protein import into mitochondria …

In this manuscript, we introduced a French EOAD patient in Korea who carried the presenilin-
1 (PSEN1) Glu318Gly mutations with four possible risk variants, including sortilin-related …

Background Mitochondrial dysfunction in kidney cells has been implicated in the
pathogenesis of chronic kidney disease (CKD). Estimation of mitochondrial DNA copy …

Background: We aimed to investigate two polymorphisms, rs8106922 and rs157580 of
TOMM40 in Alzheimer's disease (AD). Methods: In the present case-control research, we …

Aims: TOMM40 single nucleotide polymorphism (SNP) rs2075650 consists of allelic
variation c. 275-31A> G and it has been linked to Alzheimer disease, apolipoprotein and …

Osteosarcoma (OS) is the most common malignancy in children and adolescents and has a
high probability of recurrence and metastasis. A growing number of studies have shown that …

Mitochondrial dysfunction is a central aspect of Parkinson's disease (PD) pathology, yet the
underlying mechanisms are not fully understood. This study investigates the link between α …

The gene encoding TOMM40 (Transporter of Outer Mitochondrial Membrane 40) is adjacent
to that encoding APOE, which has a central role in lipid and lipoprotein metabolism. Human …

Аннотация С ростом продолжительности жизни происходит увеличение количества
пожилых людей среди населения, поэтому важной задачей для российского …