[HTML][HTML] Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …

[HTML][HTML] COVID-19-associated neurological disorders: the potential route of CNS invasion and blood-brain barrier relevance

A Achar, C Ghosh - Cells, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human
coronavirus that has sparked a global pandemic of the coronavirus disease of 2019 (COVID …

Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial

MI Lopes, LP Bonjorno, MC Giannini, NB Amaral… - RMD open, 2021 - rmdopen.bmj.com
Objective To evaluate whether the addition of colchicine to standard treatment for COVID-19
results in better outcomes. Design We present the results of a randomised, double-blinded …

[HTML][HTML] Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19

C Liu, AJ Martins, WW Lau, N Rachmaninoff, J Chen… - Cell, 2021 - cell.com
COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response
variation to disease severity and outcome over time, we longitudinally assessed circulating …

[HTML][HTML] Role of interleukin 6 as a predictive factor for a severe course of Covid-19: retrospective data analysis of patients from a long-term care facility during Covid-19 …

P Sabaka, A Koščálová, I Straka, J Hodosy… - BMC infectious …, 2021 - Springer
Background Covid-19 is a disease with high morbidity and mortality among elderly residents
of long-term care facilities (LTCF). During an outbreak of SARS-CoV-2 infection in the LTCF …

[HTML][HTML] Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: A review

BM Liu, TB Martins, LK Peterson, HR Hill - Cytokine, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a rapidly evolving infectious/inflammatory
disorder which has turned into a global pandemic. With severe acute respiratory syndrome …

Association between IL-6 and severe disease and mortality in COVID-19 disease: a systematic review and meta-analysis

X Liu, H Wang, S Shi, J Xiao - Postgraduate medical journal, 2022 - academic.oup.com
Abstract Background So far, SARS-CoV-2 is the seventh coronavirus found to infect humans
and cause disease with quite a strong infectivity. Patients diagnosed as severe or critical …

[HTML][HTML] Honeysuckle (Lonicera japonica) and Huangqi (Astragalus membranaceus) Suppress SARS-CoV-2 Entry and COVID-19 Related Cytokine Storm in Vitro

YC Yeh, LH Doan, ZY Huang, LW Chu… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is threatening human health worldwide but no effective treatment currently exists
for this disease. Current therapeutic strategies focus on the inhibition of viral replication or …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …