FGFR families: biological functions and therapeutic interventions in tumors

Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …

The role of gut microbiota and drug interactions in the development of colorectal cancer

J Wu, C Xia, C Liu, Q Zhang, C Xia - Frontiers in Pharmacology, 2023 - frontiersin.org
The human gut microbiota is a complex ecosystem regulating the host's environmental
interaction. The same functional food or drug may have varying bioavailability and distinct …

Phytochemicals for the prevention and treatment of pancreatic cancer: Current progress and future prospects

N Casarcia, P Rogers, E Guld, S Iyer… - British Journal of …, 2023 - Wiley Online Library
Pancreatic cancer is the third leading cause of cancer‐related deaths in the United States,
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …

Butyrate's (a short-chain fatty acid) microbial synthesis, absorption, and preventive roles against colorectal and lung cancer

MR Karim, S Iqbal, S Mohammad, MN Morshed… - Archives of …, 2024 - Springer
Butyrate, a short-chain fatty acid (SCFA) produced by bacterial fermentation of fiber in the
colon, is a source of energy for colonocytes. Butyrate is essential for improving …

Identification of a brand intratumor microbiome signature for predicting prognosis of hepatocellular carcinoma

Y Song, Z Xiang, Z Lu, R Su, W Shu, M Sui… - Journal of Cancer …, 2023 - Springer
Purpose Given that prognosis of hepatocellular carcinoma (HCC) differs dramatically, it is
imperative to uncover effective and available prognostic biomarker (s). The intratumor …

Insights into the oral microbiota in human systemic cancers

L Su, R Yang, Y Sheng, S Ullah, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
The oral cavity stands as one of the pivotal interfaces facilitating the intricate interaction
between the human body and the external environment. The impact of diverse oral …

Advancements in the impact of human microbiota and probiotics on leukemia

Y Zhang, X Zhao, J Zhang, Y Zhang, Y Wei - Frontiers in Microbiology, 2024 - frontiersin.org
The human gut microbiota is a complex ecosystem that plays a crucial role in promoting the
interaction between the body and its environment. It has been increasingly recognized that …

Role of the Microbiota in Skin Neoplasms: New Therapeutic Horizons

P Savoia, B Azzimonti, R Rolla, E Zavattaro - Microorganisms, 2023 - mdpi.com
The skin and the gut are regularly colonized by a variety of microorganisms capable of
interacting with the immune system through their metabolites and influencing the balance …

The crosstalk between SUMOylation and immune system in host-pathogen interactions

G Zhu, N Tong, Y Zhu, L Wang… - Critical Reviews in …, 2024 - Taylor & Francis
Pathogens can not only cause infectious diseases, immune system diseases, and chronic
diseases, but also serve as potential triggers or initiators for certain tumors. They directly or …

Cervicovaginal microbiota: a promising direction for prevention and treatment in cervical cancer

J Shen, H Sun, J Chu, X Gong, X Liu - Infectious Agents and Cancer, 2024 - Springer
Cervical cancer is a common malignancy in women, with high incidence rate and mortality.
Persistent infection of high-risk human papillomavirus (HPV) is the most important risk factor …