On the computational modeling of the innate immune system
AB Pigozzo, GC Macedo, RW Dos Santos… - BMC …, 2013 - Springer
In recent years, there has been an increasing interest in the mathematical and
computational modeling of the human immune system (HIS). Computational models of HIS …
computational modeling of the human immune system (HIS). Computational models of HIS …
Toward predicting the spatio-temporal dynamics of alopecia areata lesions using partial differential equation analysis
A Dobreva, R Paus, NG Cogan - Bulletin of mathematical biology, 2020 - Springer
Hair loss in the autoimmune disease, alopecia areata (AA), is characterized by the
appearance of circularly spreading alopecic lesions in seemingly healthy skin. The distinct …
appearance of circularly spreading alopecic lesions in seemingly healthy skin. The distinct …
Optimal antimicrobial response to a changing microbial background at a mucus interface
Complex lifeforms host microbiota, microbes that live synergistically with their host.
Accordingly, hosts have mechanisms to defend against and tolerate the microbiota. The …
Accordingly, hosts have mechanisms to defend against and tolerate the microbiota. The …
On the coupling of two models of the human immune response to an antigen
BM Quintela, RW dos Santos… - BioMed research …, 2014 - Wiley Online Library
The development of mathematical models of the immune response allows a better
understanding of the multifaceted mechanisms of the defense system. The main purpose of …
understanding of the multifaceted mechanisms of the defense system. The main purpose of …
[HTML][HTML] A multiscale hybrid model for exploring the effect of Resolvin D1 on macrophage polarization during acute inflammation
Dysregulated inflammation underlies various diseases. Specialized pro-resolving mediators
(SPMs) like Resolvin D1 (RvD1) have been shown to resolve inflammation and halt disease …
(SPMs) like Resolvin D1 (RvD1) have been shown to resolve inflammation and halt disease …
Computational modeling of microabscess formation
AB Pigozzo, GC Macedo… - … methods in medicine, 2012 - Wiley Online Library
Bacterial infections can be of two types: acute or chronic. The chronic bacterial infections are
characterized by being a large bacterial infection and/or an infection where the bacteria …
characterized by being a large bacterial infection and/or an infection where the bacteria …
Immune system model calibration by genetic algorithm
We aim to develop a mathematical model of the human immune system for advanced
individualized healthcare where medication plan is fine-tuned to fit a patient's conditions …
individualized healthcare where medication plan is fine-tuned to fit a patient's conditions …
A three-dimensional computational model of the innate immune system
PAF Rocha, MP Xavier, AB Pigozzo… - … Science and Its …, 2012 - Springer
Abstract The Human Immune System is a complex system responsible for protecting the
organism against diseases. Although understanding how it works is essential to develop …
organism against diseases. Although understanding how it works is essential to develop …
[PDF][PDF] Using mathematical tools to investigate the autoimmune hair loss disease alopecia areata
A Dobreva - 2018 - diginole.lib.fsu.edu
Alopecia areata is an autoimmune condition where the immune system attacks hair follicles
and disrupts their natural cycle through phases of growth, regression, and rest. The disease …
and disrupts their natural cycle through phases of growth, regression, and rest. The disease …
Modelling the innate immune system
P Rocha, A Pigozzo, B Quintela… - … Algorithms and their …, 2012 - books.google.com
The Human Immune System (HIS) is a complex network composed of specialized cells,
tissues, and organs that is responsible for protecting the organism against diseases caused …
tissues, and organs that is responsible for protecting the organism against diseases caused …