Corneal confocal microscopy detects improvement in corneal nerve morphology with an improvement in risk factors for diabetic neuropathy

M Tavakoli, P Kallinikos, A Iqbal, A Herbert… - Diabetic …, 2011 - Wiley Online Library
Diabet. Med. 28, 1261–1267 (2011) Abstract Aim We have assessed whether corneal
confocal microscopy can be used to detect alterations in nerve morphology following an …

Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy

WZ So, NSQ Wong, HC Tan, MTY Lin… - Neural Regeneration …, 2022 - journals.lww.com
Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting
nerves in all parts of the body including corneal nerves and peripheral nervous system …

Corneal confocal microscopy: a novel non-invasive technique to quantify small fibre pathology in peripheral neuropathies

M Tavakoli, RA Malik - JoVE (Journal of Visualized Experiments), 2011 - jove.com
The accurate quantification of peripheral neuropathy is important to define at risk patients,
anticipate deterioration, and assess new therapies. Conventional methods assess …

[HTML][HTML] The ocular surface and diabetes, the other 21st Century epidemic

Y Bu, KC Shih, L Tong - Experimental Eye Research, 2022 - Elsevier
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by sustained
hyperglycemia, potentially leading to life-threatening health problems. While the …

Use of corneal confocal microscopy to detect corneal nerve loss and increased dendritic cells in patients with multiple sclerosis

G Bitirgen, Z Akpinar, RA Malik… - JAMA …, 2017 - jamanetwork.com
Importance Multiple sclerosis (MS) is characterized by demyelination, axonal degeneration,
and inflammation. Corneal confocal microscopy has been used to identify axonal …

Corneal confocal microscopy for assessment of diabetic peripheral neuropathy: a meta-analysis

MS Jiang, Y Yuan, ZX Gu, SL Zhuang - British Journal of …, 2016 - bjo.bmj.com
Purpose To evaluate the diagnostic performance of corneal confocal microscopy (CCM) in
assessing corneal nerve parameters in patients with diabetic peripheral neuropathy (DPN) …

Evolving concepts on the role of dyslipidemia, bioenergetics, and inflammation in the pathogenesis and treatment of diabetic peripheral neuropathy

AM Stino, AE Rumora, B Kim… - Journal of the Peripheral …, 2020 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is one of the most widespread and disabling
neurological conditions, accounting for half of all neuropathy cases worldwide. Despite its …

Longitudinal assessment of small fiber neuropathy: evidence of a non–length-dependent distal axonopathy

MA Khoshnoodi, S Truelove, A Burakgazi… - JAMA …, 2016 - jamanetwork.com
Importance Few data are available on the natural history of small fiber neuropathy (SNF).
Peripheral neuropathy typically follows a length-dependent pattern, leading us to …

Reproducibility of in vivo corneal confocal microscopy as a novel screening test for early diabetic sensorimotor polyneuropathy

P Hertz, V Bril, A Orszag, A Ahmed, E Ng… - Diabetic …, 2011 - Wiley Online Library
Diabet. Med. 28, 1253–1260 (2011) Abstract Aim With the goal of identifying a valid
biomarker of early diabetic sensorimotor polyneuropathy, we aimed to identify the most …

Efficacy of autologous serum tears for treatment of neuropathic corneal pain

S Aggarwal, C Colon, A Kheirkhah, P Hamrah - The ocular surface, 2019 - Elsevier
Objective Corneal nerve damage may result in neuropathic corneal pain (NCP). Autologous
serum tears (AST) have been shown to results in nerve regeneration and may help alleviate …