Repeated monitoring of corneal nerves by confocal microscopy as an index of peripheral neuropathy in type‐1 diabetic rodents and the effects of topical insulin

DK Chen, KE Frizzi, LS Guernsey… - Journal of the …, 2013 - Wiley Online Library
We developed a reliable imaging and quantitative analysis method for in vivo corneal
confocal microscopy (CCM) in rodents and used it to determine whether models of type 1 …

Small fiber neuropathy: a disabling and underrecognized syndrome

M Voortman, D Fritz, OJM Vogels… - Current opinion in …, 2017 - journals.lww.com
Awareness of SFN and related symptoms is of great clinical relevance. Guidelines for
appropriate diagnostic workup using a stepwise approach involving a combination of tests …

In vivo corneal confocal microscopy and prediction of future-incident neuropathy in type 1 diabetes: a preliminary longitudinal analysis

LE Lovblom, EM Halpern, T Wu, D Kelly… - Canadian journal of …, 2015 - Elsevier
Objective In vivo corneal confocal microscopy (IVCCM) has been established in cross-
sectional studies as a valid measure for the identification of diabetic sensorimotor …

Chronic migraine is associated with reduced corneal nerve fiber density and symptoms of dry eye

KI Kinard, AG Smith, JR Singleton… - … : The Journal of …, 2015 - Wiley Online Library
Background We used in vivo corneal confocal microscopy to investigate structural
differences in the sub‐basal corneal nerve plexus in chronic migraine patients and a normal …

In vivo confocal microscopy of the human cornea in the assessment of peripheral neuropathy and systemic diseases

EF Wang, SL Misra, DV Patel - BioMed research international, 2015 - Wiley Online Library
In vivo confocal microscopy (IVCM) of the living human cornea offers the ability to perform
repeated imaging without tissue damage. Studies using corneal IVCM have led to significant …

Corneal confocal microscopy: a new technique for early detection of diabetic neuropathy

N Papanas, D Ziegler - Current diabetes reports, 2013 - Springer
Corneal confocal microscopy (CCM) is a noninvasive method for the study of human cornea
in vivo. It has increasingly been used to assess the morphology of the sub-basal corneal …

[HTML][HTML] Cornea nerve fiber quantification and construction of phenotypes in patients with fibromyalgia

L Oudejans, X He, M Niesters, A Dahan, M Brines… - Scientific reports, 2016 - nature.com
Cornea confocal microscopy (CCM) is a novel non-invasive method to detect small nerve
fiber pathology. CCM generally correlates with outcomes of skin biopsies in patients with …

Impact of diabetes mellitus on the ocular surface: a review

SL Misra, GD Braatvedt, DV Patel - Clinical & Experimental …, 2016 - Wiley Online Library
Although diabetes mellitus is reaching epidemic proportions worldwide, ocular surface
complications are still largely believed to be uncommon. Although these complications are …

[HTML][HTML] In vivo corneal confocal microscopic analysis in patients with keratoconus

G Bitirgen, A Ozkagnici, B Bozkurt… - International Journal of …, 2015 - ncbi.nlm.nih.gov
AIM To quantify corneal ultrastructure using laser scanning in vivo confocal microscopy
(IVCM) in patients with keratoconus and control subjects. METHODS Unscarred corneas of …

Abnormalities of retinal ganglion cell complex at optical coherence tomography in patients with type 2 diabetes: a sign of diabetic polyneuropathy, not retinopathy

L Salvi, P Plateroti, S Balducci, L Bollanti… - Journal of Diabetes and …, 2016 - Elsevier
Aims To compare optical coherence tomography (OCT)-derived neuro-retinal parameters in
patients with type 2 diabetes and non-diabetic controls and to evaluate their correlation with …