A human DPP4-knockin mouse's susceptibility to infection by authentic and pseudotyped MERS-CoV
C Fan, X Wu, Q Liu, Q Li, S Liu, J Lu, Y Yang, Y Cao… - Viruses, 2018 - mdpi.com
Infection by the Middle East respiratory syndrome coronavirus (MERS-CoV) causes
respiratory illness and has a high mortality rate (~ 35%). The requirement for the virus to be …
respiratory illness and has a high mortality rate (~ 35%). The requirement for the virus to be …
Passive transfer of a germline-like neutralizing human monoclonal antibody protects transgenic mice against lethal Middle East respiratory syndrome coronavirus …
AS Agrawal, T Ying, X Tao, T Garron, A Algaissi… - Scientific reports, 2016 - nature.com
Abstract Middle East Respiratory Syndrome coronavirus (MERS-CoV) has repeatedly
caused outbreaks in the Arabian Peninsula. To date, no approved medical countermeasures …
caused outbreaks in the Arabian Peninsula. To date, no approved medical countermeasures …
Contributions of farm animals to immunology
E Guzman, M Montoya - Frontiers in veterinary science, 2018 - frontiersin.org
By their very nature, great advances in immunology are usually underpinned by experiments
carried out in animal models and inbred lines of mice. Also, their corresponding knock-out or …
carried out in animal models and inbred lines of mice. Also, their corresponding knock-out or …
Protection of human ACE2 transgenic Syrian hamsters from SARS CoV-2 variants by human polyclonal IgG from hyper-immunized transchromosomic bovines
Pandemic SARS CoV-2 has been undergoing rapid evolution during spread throughout the
world resulting in the emergence of many Spike protein variants, some of which appear to …
world resulting in the emergence of many Spike protein variants, some of which appear to …
A fully human monoclonal antibody possesses antibody‐dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a …
The DiversitabTM system produces target specific high titer fully human polyclonal IgG
immunoglobulins from transchromosomic (Tc) bovines shown to be safe and effective …
immunoglobulins from transchromosomic (Tc) bovines shown to be safe and effective …
Potential therapeutic approach of intravenous immunoglobulin against COVID-19
Z Kolahchi, H Sohrabi, S Ekrami Nasab… - Allergy, Asthma & …, 2021 - Springer
Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and
management options to reduce the burden of the COVID-19 disease are under investigation …
management options to reduce the burden of the COVID-19 disease are under investigation …
[HTML][HTML] Transchromosomic bovine-derived anti-SARS-CoV-2 polyclonal human antibodies protects hACE2 transgenic hamsters against multiple variants
Pandemic SARS-CoV-2 has undergone rapid evolution resulting in the emergence of many
variants with mutations in the spike protein, some of which appear to evade antibody …
variants with mutations in the spike protein, some of which appear to evade antibody …
Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model
Abstract Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection
caused by a coronavirus (CoV), MERS-CoV. With the continuing spread of MERS-CoV …
caused by a coronavirus (CoV), MERS-CoV. With the continuing spread of MERS-CoV …
Development of Middle East respiratory syndrome coronavirus vaccines–advances and challenges
H Cho, JL Excler, JH Kim, IK Yoon - Human Vaccines & …, 2018 - Taylor & Francis
ABSTRACT Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an emerging
pathogen with the potential to pose a threat to global public health. Sporadic cases and …
pathogen with the potential to pose a threat to global public health. Sporadic cases and …