Managing end-stage renal disease in the elderly: state-of-the-art, challenges and opportunities

C Somma, M Trillini, M Kasa, G Gentile - Aging health, 2013 - Taylor & Francis
The global population is progressively aging, to the extent that over 1.5 billion people
worldwide will be aged 65 years or more by 2050, and the prevalence of end-stage renal …

Role of the kisspeptin-KISS1R axis in the pathogenesis of chronic kidney disease and uremic cardiomyopathy

H Dinh, ZZA Kovács, M Kis, K Kupecz, A Sejben… - GeroScience, 2024 - Springer
The prevalence of chronic kidney disease (CKD) is increasing globally, especially in elderly
patients. Uremic cardiomyopathy is a common cardiovascular complication of CKD …

Spectrum and prognosis of renal histopathological lesions in patients with inflammatory bowel disease: a cross-sectional study from a single center in China

L Zhao, G Ren, R Fan, X Feng, Z Liu, Z Cheng… - Clinical and …, 2021 - Springer
To explore the spectrum, clinicopathological features and prognosis of patients with
inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) …

Chronic arachidonic acid administration decreases docosahexaenoic acid-and eicosapentaenoic acid-derived metabolites in kidneys of aged rats

M Katakura, M Hashimoto, T Inoue, AA Mamun… - PLoS …, 2015 - journals.plos.org
Arachidonic acid (ARA) metabolites produced by cyclo-oxygenase and lipoxygenase are
important mediators maintaining physiological renal function. However, the effects of …

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker on oxidative stress and metabolism of elements in kidney of STZ-induced diabetic …

NP Özsobacı, M Karataş, M Tuncdemir… - Archives of Biochemistry …, 2024 - Elsevier
In diabetes, increased oxidative stress and impaired trace element metabolism play an
important role in the pathogenesis of diabetic nephropathy. The objective of this research …

[HTML][HTML] Fibrosis-4 Score Is Associated with Mortality in Hemodialysis Patients with Chronic Viral Hepatitis: A Retrospective Study

HH Liu, CL Yen, WJ Jeng, CC Hung, CC Hsiao… - Diagnostics, 2024 - mdpi.com
BACKGROUND: Chronic hepatitis B and C infections are major causes of morbidity and
mortality in end-stage kidney disease (ESKD) patients on hemodialysis (HD). The Fibrosis-4 …

S-carbamoylation impairs the oxidant scavenging activity of cysteine: its possible impact on increased LDL modification in uraemia

SM Schreier, H Steinkellner, L Jirovetz, M Hermann… - Biochimie, 2011 - Elsevier
Carbamoylation is the non-enzymatic reaction of cyanate with amino-, hydroxy-or thiol
groups. In vivo, amino group modification (N-carbamoylation) resulting in altered function of …

Roles of telomeres and telomerase in age‑related renal diseases

H Li, B Wang, D Li, J Li, Y Luo… - Molecular Medicine …, 2021 - spandidos-publications.com
Age‑related renal diseases, which account for various progressive renal disorders
associated with cellular and organismal senescence, are becoming a substantial public …

Gamma-oryzanol reduces renal inflammation and oxidative stress by modulating AGEs/RAGE axis in animals submitted to high sugar-fat diet

FV Francisqueti-Ferron, AJT Ferron… - Brazilian Journal of …, 2021 - SciELO Brasil
Abstract Introduction: The receptor for AGEs (RAGE) is a multiligand member of the
immunoglobulin superfamily of cell surface receptors expressed in many organs, among …

Irbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular …

T Matsui, Y Nishino, S Maeda, M Takeuchi… - Microvascular …, 2011 - Elsevier
Renin–angiotensin system (RAS) plays a central role in the development and progression of
diabetic nephropathy. There is a growing body of evidence that advanced glycation end …