Environmental causes of idiopathic pulmonary fibrosis

S Gandhi, R Tonelli, M Murray, AV Samarelli… - International Journal of …, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF), the most common and severe of the idiopathic interstitial
pneumonias, is a chronic and relentlessly progressive disease, which occurs mostly in …

Interstitial lung disease and sarcoidosis

M Sharp, AM Mustafa, N Farah… - Clinics in Chest …, 2023 - chestmed.theclinics.com
Interstitial lung disease (ILD) is a clinically recognized group of diseases that all result in the
scarring of the lung interstitium, also termed pulmonary fibrosis. 1, 2 Causes of ILD vary from …

Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development

S Piñeiro-Hermida, P Martínez, G Bosso… - Nature …, 2022 - nature.com
TRF1 is an essential component of the telomeric protective complex or shelterin. We
previously showed that dysfunctional telomeres in alveolar type II (ATII) cells lead to …

[HTML][HTML] Unusual X chromosome inactivation maintenance in female alveolar type 2 cells is correlated with increased numbers of X-linked escape genes and sex …

I Sierra, S Pyfrom, A Weiner, G Zhao, A Driscoll, X Yu… - Stem Cell Reports, 2023 - cell.com
Sex differences exist for many lung pathologies, including COVID-19 and pulmonary
fibrosis, but the mechanistic basis for this remains unclear. Alveolar type 2 cells (AT2s) …

Lung mechanics showing sex‐based differences and circadian time‐of‐day response to bleomycin‐induced lung injury in mice

C Prasad, SK Duraisamy, IK Sundar - Physiological Reports, 2023 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that impairs lung mechanical
properties due to dysregulated extracellular matrix remodeling. Lung function assessment is …

Associations between the use of common nonsteroidal anti-inflammatory drugs, genetic susceptibility and dementia in participants with chronic pain: A prospective …

S Yuan, Y Ling, X Huang, S Tan, W Li, A Xu… - Journal of Psychiatric …, 2024 - Elsevier
Objective To investigate the potential relationship between common nonsteroidal anti-
inflammatory drugs (NSAIDs), genetic susceptibility and all-cause dementia (ACD) …

Interstitial lung disease: a review of classification, etiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment

MA Althobiani, AM Russell, J Jacob, Y Ranjan… - Frontiers in …, 2024 - frontiersin.org
Interstitial lung diseases (ILDs) refer to a heterogeneous and complex group of conditions
characterized by inflammation, fibrosis, or both, in the interstitium of the lungs. This results in …

Impact of sex and gender on autoimmune lung disease: opportunities for future research: NHLBI working group report

ER Volkmann, J Siegfried, T Lahm… - American journal of …, 2022 - atsjournals.org
Understanding the roles of sex and gender in autoimmune lung diseases is central to the
advancement of science in this field. Although it is well known that most autoimmune …

Sex Difference in Primary Sjögren Syndrome: A Medical Records Review Study

Y Zhang, JQ Chen, JY Yang, JH Liao… - JCR: Journal of …, 2023 - journals.lww.com
Objectives The aim of this study was to study clinical and biological differences between
men and women with primary Sjögren syndrome (pSS) in China and perform a literature …

Beyond the Lungs: O2 Supplementation Improves Cerebral Oxygenation and Fatigue during Exercise in Interstitial Lung Disease.

M Marillier, M Gruet, AC Bernard… - … and Science in …, 2023 - europepmc.org
Purpose Cerebral hypoxia may exacerbate the perception of fatigue. We previously
demonstrated that exercise-related hypoxemia, a hallmark of fibrotic interstitial lung disease …