The insights of microbes' roles in wound healing: A comprehensive review

T Maheswary, AA Nurul, MB Fauzi - Pharmaceutics, 2021 - mdpi.com
A diverse range of normal flora populates the human skin and numbers are relatively
different between individuals and parts of the skin. Humans and normal flora have formed a …

The expanded role of chitosan in localized antimicrobial therapy

LM Hemmingsen, N Škalko-Basnet, MW Jøraholmen - Marine Drugs, 2021 - mdpi.com
Chitosan is one of the most studied natural origin polymers for biomedical applications. This
review focuses on the potential of chitosan in localized antimicrobial therapy to address the …

Zika virus spreads through infection of lymph node-resident macrophages

GV Reynoso, DN Gordon, A Kalia, CC Aguilar… - Cell reports, 2023 - cell.com
To disseminate through the body, Zika virus (ZIKV) is thought to exploit the mobility of
myeloid cells, in particular monocytes and dendritic cells. However, the timing and …

Autophagy: guardian of skin barrier

HJ Kim, J Park, SK Kim, H Park, JE Kim, S Lee - Biomedicines, 2022 - mdpi.com
Autophagy is a major degradation pathway that removes harmful intracellular substances to
maintain homeostasis. Various stressors, such as starvation and oxidative stress, upregulate …

Dermatologic Changes in Experimental Model of Long COVID

H Hussain, MJ Paidas, R Rajalakshmi, A Fadel, M Ali… - Microorganisms, 2024 - mdpi.com
The coronavirus disease-19 (COVID-19) pandemic, declared in early 2020, has left an
indelible mark on global health, with over 7.0 million deaths and persistent challenges …

[HTML][HTML] Challenges and progress related to gene editing in rare skin diseases

J Piñón-Hofbauer, C Guttmann-Gruber, V Wally… - Advanced Drug Delivery …, 2024 - Elsevier
Genodermatoses represent a large group of inherited skin disorders encompassing
clinically-heterogeneous conditions that manifest in the skin and other organs. Depending …

Cowpox viruses: a zoo full of viral diversity and lurking threats

RC Bruneau, L Tazi, S Rothenburg - Biomolecules, 2023 - mdpi.com
Cowpox viruses (CPXVs) exhibit the broadest known host range among the Poxviridae
family and have caused lethal outbreaks in various zoo animals and pets across 12 …

Insight into oncogenic viral pathways as drivers of viral cancers: implication for effective therapy

AME Elkhalifa, SU Nabi, OS Shah, SM Bashir… - Current …, 2023 - mdpi.com
As per a recent study conducted by the WHO, 15.4% of all cancers are caused by infectious
agents of various categories, and more than 10% of them are attributed to viruses. The …

[HTML][HTML] Immune responses to viruses

SN Mueller, BT Rouse - Clinical Immunology, 2008 - ncbi.nlm.nih.gov
Viruses as obligate intracellular parasites require their host to replicate them and to facilitate
their spread to others. In humans, viral infections are rarely lethal, even if they are highly …

T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

JC Harbour, M Abdelbary, JB Schell, SP Fancher… - Cell reports, 2023 - cell.com
Poxvirus infections of the skin are a recent emerging public health concern, yet the
mechanisms that mediate protective immunity against these viral infections remain largely …