The major component of senile plaques and vascular amyloid in Alzheimer's disease (AD)
brains is the amyloid β protein (Aβ). Besides Aβ, several other proteins have been identified …

Amyloidogenic proteins have the characteristic of adopting a β-sheet conformation and
assembling into fibrils. Although similar in fibrillar appearance, each type of peripheral …

Aggregation and deposition of misfolded amyloid-β (Aβ) peptide in the brain is central to
Alzheimer's disease (AD). Oligomeric, protofibrillar, and fibrillar forms of Aβ are believed to …

Regenerative responses, including re‐expression of developmentally regulated proteins,
occur in Alzheimer's disease (AD) brain and in β‐amyloid (Aβ)‐treated neuronal cultures …

β-amyloid (Aβ) is presumed to play a pathogenic role in Alzheimer's disease (AD). However,
there is an imperfect correlation between Aβ deposition and neuronal loss or dementia. To …

Alzheimer's disease (AD) is characterized by cerebral proteinaceous deposits comprised of
amyloid beta (Aβ). Evidence suggests that enhanced blood-to-brain delivery of Aβ occurs …

Background: The cystic fibrosis transmembrane conductance regulator (CFTR) gene
encodes a~ 150–165 kD glycoprotein that is mutated in individuals with cystic fibrosis …

Alzheimer's disease (AD) is the most common form of dementia. Currently, there is no
effective treatment for AD, as its etiology remains poorly understood. Mounting evidence …

The need for effective treatments halting Alzheimer's disease (AD) urges the discovery of the
earliest possible biomarkers. Agrin is increased in the early stages of AD and is involved in …