Abstract N-acetyl-L-cysteine (NAC) is a compound of increasing interest in the treatment of
psychiatric disorders. Primarily through its antioxidant, anti-inflammatory, and glutamate …

Recent studies have found that hundreds of genetic variants, including common and rare
variants, rare and de novo mutations, and common polymorphisms contribute to the …

Autism spectrum disorder (ASD) is induced by complex hereditary and environmental
factors. However, the mechanisms of ASD development are poorly understood. The purpose …

N‐acetylcysteine (NAC) is a well‐known and safe mucolytic agent, also used in patients with
paracetamol overdose. In addition to these effects, recent preclinical and clinical studies …

Objective: Currently, pharmaceutical treatment options for autism spectrum disorder are
limited. Brain glutaminergic dysregulation is observed in autism spectrum disorder. N …

Synapses are complex structures that allow communication between neurons in the central
nervous system. Studies conducted in vertebrate and invertebrate models have contributed …

Autism is characterized by atypical social communication and stereotyped behaviors.
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are detected in 1 …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
persistent deficits in social communication and interaction and restricted, repetitive patterns …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with a
high prevalence rate. The core symptoms of ASD patients are impaired social …

Rationale Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized
by impaired social interaction and restricted/stereotyped behavior. Prenatal exposure to …