Immunological dimensions of neuroinflammation and microglial activation: exploring innovative immunomodulatory approaches to mitigate neuroinflammatory …

L Fornari Laurindo, J Aparecido Dias… - Frontiers in …, 2024 - frontiersin.org
The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy

J Han, J Lim, CPJ Wang, JH Han, HE Shin, SN Kim… - Nano …, 2023 - Springer
Cancer immunotherapy, which harnesses the power of the immune system, has shown
immense promise in the fight against malignancies. Messenger RNA (mRNA) stands as a …

Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

HC Hawerkamp, AH Dyer, ND Patil… - Frontiers in …, 2023 - frontiersin.org
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …

Recombinant SARS-CoV-2 spike protein stimulates secretion of chymase, tryptase, and IL-1β from human mast cells, augmented by IL-33

I Tsilioni, TC Theoharides - International Journal of Molecular Sciences, 2023 - mdpi.com
SARS-CoV-2 infects cells via its spike (S) protein binding to its surface receptor angiotensin-
converting enzyme 2 (ACE2) and results in the production of multiple proinflammatory …

The Important Role of Interleukin‐2 in COVID‐19

L Ghanbari Naeini, L Abbasi, F Karimi… - Journal of …, 2023 - Wiley Online Library
There is controversial literature about the effects of the interleukin‐2 (IL‐2) cytokine family in
COVID‐19 pathogenesis and immunity. So we aimed to identify the potential in the role of …

Cytokine profiling in different SARS-CoV-2 genetic variants

ZR Korobova, NA Arsentieva, NE Liubimova… - International Journal of …, 2022 - mdpi.com
This study is a successor of our previous work concerning changes in the chemokine profile
in infection that are associated with different SARS-CoV-2 genetic variants. The goal of our …

IL-33 and IL-37: a possible Axis in skin and allergic diseases

F Borgia, P Custurone, F Li Pomi, M Vaccaro… - International Journal of …, 2022 - mdpi.com
Interleukin (IL)-37 and IL-33 are among the latest cytokines identified, playing a role in
several inflammatory conditions, spanning from systemic conditions to tumors to localized …

Deciphering the fibrotic process: mechanism of chronic radiation skin injury fibrosis

Y Wang, S Chen, S Bao, L Yao, Z Wen, L Xu… - Frontiers in …, 2024 - frontiersin.org
This review explores the mechanisms of chronic radiation-induced skin injury fibrosis,
focusing on the transition from acute radiation damage to a chronic fibrotic state. It reviewed …

[HTML][HTML] The favorable impacts of silibinin polyphenols as adjunctive therapy in reducing the complications of COVID-19: A review of research evidence and …

V Musazadeh, A Karimi, J Jafarzadeh, S Sanaie… - Biomedicine & …, 2022 - Elsevier
The proceeding pandemic of coronavirus disease 2019 is the latest global challenge. Like
most other infectious diseases, inflammation, oxidative stress, and immune system …

Serum profiles of pro-inflammatory and anti-inflammatory cytokines in non-hospitalized patients with mild/moderate COVID-19 infection.

AY Majeed, NES Zulkafli, AH Ad'hiah - Immunology Letters, 2023 - Elsevier
This study attempted to explore pro-inflammatory and anti-inflammatory responses in
patients with mild/moderate coronavirus disease 19 (COVID-19). Eight pro-inflammatory (IL …