The accumulation of cholesterol is a general feature of cancer tissue, and recent evidence
suggests that cholesterol plays critical roles in the progression of cancers, including breast …

MicroRNAs (miRNAs) interfere with the translation of specific target mRNAs and are thought
to thereby regulate many cellular processes. However, the role of miRNAs in osteoblast …

The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

MicroRNAs are short noncoding RNAs, expressed in humans and involved in sequence-
specific post-transcriptional regulation of gene expression. They have emerged as key …

Atherosclerosis is a complex multifactorial disease that, despite advances in lifestyle
management and drug therapy, remains to be the major cause of high morbidity and …

Pathologic angiogenesis mediated by abnormally polarized macrophages plays a central
role in common age-associated diseases such as atherosclerosis, cancer, and macular …

High glycolysis, well known as" Warburg effect," is frequently observed in a variety of
cancers. Whether the deregulation of miRNAs contributes to the Warburg effect remains …

In the mouse liver, circadian transcriptional rhythms are necessary for metabolic
homeostasis. Whether dynamic epigenomic modifications are associated with transcript …

Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular
diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse …

Cellular and plasma lipid levels are tightly controlled by complex gene regulatory
mechanisms. Elevated plasma lipid content, or hyperlipidemia, is a significant risk factor for …