This review examines mechanisms by which the bacteria present in the gut interact with
nutrients and host biology to affect the risk of obesity and associated disorders, including …

The etiology of dental caries remains elusive because of our limited understanding of the
complex oral microbiomes. The current methodologies have been limited by insufficient …

Over the past decade, high-throughput short-read 16S rRNA gene amplicon sequencing has
eclipsed clone-dependent long-read Sanger sequencing for microbial community profiling …

Over the course of our lives, humans are colonized by a tremendous diversity of commensal
microbes, which comprise the human microbiome. The collective genetic potential …

The upper respiratory tract (URT) is a crucial site for host defense, as it is home to bacterial
communities that both modulate host immune defense and serve as a reservoir of potential …

Bacterial ocular infections are common. Traditional culture and molecular biological
methods have obvious limitations to identify the conjunctival microbiota, while metagenomic …

The present study applied both metagenomic and metatranscriptomic approaches to
characterize microbial structure and gene expression of an activated sludge community from …

Recovery of ribosomal small subunit genes by assembly of short read community DNA
sequence data generally fails, making taxonomic characterization difficult. Here, we solve …

Alzheimer's disease (AD) is a progressive neurodegenerative pathology affecting milions of
people worldwide associated with deposition of senile plaques. While the genetic and …

Abstract Background The International Space Station (ISS) is a unique built environment
due to the effects of microgravity, space radiation, elevated carbon dioxide levels, and …