Background Hyperlipidemia-induced vascular smooth muscle cell (VSMC)-derived foam cell
formation is considered a crucial event in the development of atherosclerosis. Since c-Fos …

Oxymatrine, a quinolizidine alkaloid isolated from the traditional Chinese herb Sophora
flavescens Aiton, has been demonstrated to exert anti‑inflammatory and atherosclerotic …

Atherosclerosis (AS) constitutes a major threat to human health, yet most current
therapeutics are hindered in achieving desirable clinical outcomes by low bioavailability or …

Polyphenols found in fruits and vegetables are associated with a reduced incidence of
cardiovascular disease (CVD), the leading cause of death in the USA. Our lab demonstrated …

Atherosclerosis (AS) is a life-threatening vascular disease. RNA N6-methyladenosine (m6A)
modification level is dysregulated in multiple pathophysiologic processes including AS. In …

Objective: Systemic immune-inflammation index (SII), derived from blood cell counts of
circulating platelets, neutrophils and lymphocytes, has been identified as a novel …

Tea has long been valued for its health benefits, especially its potential to prevent and treat
atherosclerosis (AS). Abnormal lipid metabolism and oxidative stress are major factors that …

Atherosclerosis, a disease process characterized by lipid accumulation and inflammation, is
the main cause of coronary heart disease (CHD) and myocardial infarction (MI) …

Hyperlipidemia characterized by abnormal deposition of cholesterol in arteries can cause
atherosclerosis and coronary artery occlusion, leading to atherosclerotic coronary heart …

Dietary cholesterol has been a topic of debate since the 1960s when the first dietary
guidelines that limited cholesterol intake to no more than 300 mg/day were set. These …