[HTML][HTML] Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review

MS Mulani, EE Kamble, SN Kumkar… - Frontiers in …, 2019 - frontiersin.org
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

[HTML][HTML] Phage therapy in the resistance era: where do we stand and where are we going?

T Luong, AC Salabarria, DR Roach - Clinical therapeutics, 2020 - Elsevier
Purpose Widespread antibiotic-resistant bacteria are threatening the arsenal of existing
antibiotics. Not only are antibiotics less likely to be effective today, but their extensive use …

Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth

ST Abedon, KM Danis-Wlodarczyk, DJ Wozniak - Pharmaceuticals, 2021 - mdpi.com
Phage therapy is the use of bacterial viruses as antibacterial agents. A primary
consideration for commercial development of phages for phage therapy is the number of …

[HTML][HTML] Biotechnological applications of bacteriophages: State of the art

LK Harada, EC Silva, WF Campos, FS Del Fiol… - Microbiological …, 2018 - Elsevier
Bacteriophage particles are the most abundant biological entities on our planet, infecting
specific bacterial hosts in every known environment and being major drivers of bacterial …

Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Wall teichoic acid in Staphylococcus aureus host interaction

R van Dalen, A Peschel, NM van Sorge - Trends in microbiology, 2020 - cell.com
Staphylococcus aureus is a major opportunistic human pathogen that frequently causes
disease in community and hospital settings. Nasal colonization is an important risk factor for …

Bacteriophage–a promising alternative measure for bacterial biofilm control

F Tian, J Li, A Nazir, Y Tong - Infection and Drug Resistance, 2021 - Taylor & Francis
Bacterial biofilms can enhance bacteria's viability by providing resistance against antibiotics
and conventional disinfectants. The existence of biofilm is a serious threat to human health …

Design and Preclinical Development of a Phage Product for the Treatment of Antibiotic-Resistant Staphylococcus aureus Infections

SM Lehman, G Mearns, D Rankin, RA Cole, F Smrekar… - Viruses, 2019 - mdpi.com
Bacteriophages, viruses that only kill specific bacteria, are receiving substantial attention as
nontraditional antibacterial agents that may help alleviate the growing antibiotic resistance …

[HTML][HTML] The resurgence of phage-based therapy in the era of increasing antibiotic resistance: from research progress to challenges and prospects

NJ Anyaegbunam, CC Anekpo… - Microbiological …, 2022 - Elsevier
Phage therapy was implemented almost a century ago but was subsequently abandoned
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …

The perfect bacteriophage for therapeutic applications—a quick guide

L Fernández, D Gutiérrez, P García, A Rodríguez - Antibiotics, 2019 - mdpi.com
The alarming spread of multiresistant infections has kick-started the quest for alternative
antimicrobials. In a way, given the steady increase in untreatable infectious diseases …