A critical evaluation of the p-factor literature

AL Watts, AL Greene, W Bonifay, EI Fried - Nature Reviews Psychology, 2024 - nature.com
The p-factor is a construct that is thought to explain and maybe even cause variation in all
forms of psychopathology. Since its 'discovery'in 2012, hundreds of studies have been …

[HTML][HTML] Transdiagnostic biomarkers of mental illness across the lifespan: a systematic review examining the genetic and neural correlates of latent transdiagnostic …

N Hoy, SJ Lynch, MA Waszczuk, S Reppermund… - Neuroscience & …, 2023 - Elsevier
This systematic review synthesizes evidence from research investigating the biological
correlates of latent transdiagnostic dimensions of psychopathology (eg, the p-factor …

Hierarchical models of psychopathology: Empirical support, implications, and remaining issues

BB Lahey, TM Moore, AN Kaczkurkin… - World …, 2021 - Wiley Online Library
There is an ongoing revolution in psychology and psychiatry that will likely change how we
conceptualize, study and treat psychological problems. Many theorists now support viewing …

Improving parenting, child attachment, and externalizing behaviors: Meta-analysis of the first 25 randomized controlled trials on the effects of video-feedback …

MH Van Ijzendoorn, C Schuengel, Q Wang… - Development and …, 2023 - cambridge.org
Improving parenting, child attachment, and externalizing behaviors: Meta-analysis of the first
25 randomized controlled trials on the effects of Video-feedback Intervention to promote …

[HTML][HTML] The P-factor and its genomic and neural equivalents: an integrated perspective

E Sprooten, B Franke, CU Greven - Molecular Psychiatry, 2022 - nature.com
Different psychiatric disorders and symptoms are highly correlated in the general population.
A general psychopathology factor (or “P-factor”) has been proposed to efficiently describe …

White matter injury and neurodevelopmental disabilities: A cross-disease (dis) connection

E Cainelli, F Arrigoni, L Vedovelli - Progress in neurobiology, 2020 - Elsevier
White matter (WM) injury, once known primarily in preterm newborns, is emerging in its non-
focal (diffused), non-necrotic form as a critical component of subtle brain injuries in many …

[HTML][HTML] Transdiagnostic neuroimaging markers of psychiatric risk: A narrative review

LD Vanes, RJ Dolan - NeuroImage: Clinical, 2021 - Elsevier
Several decades of neuroimaging research in psychiatry have shed light on structural and
functional neural abnormalities associated with individual psychiatric disorders. However …

Neural substrates of motivational dysfunction across neuropsychiatric conditions: Evidence from meta-analysis and lesion network mapping

C Feng, W Huang, K Xu, JL Stewart, JA Camilleri… - Clinical psychology …, 2022 - Elsevier
Motivational dysfunction constitutes one of the fundamental dimensions of psychopathology
cutting across traditional diagnostic boundaries. However, it is unclear whether there is a …

The relationship between brain structure and general psychopathology in preadolescents

L Mewton, B Lees, LM Squeglia… - Journal of Child …, 2022 - Wiley Online Library
Background An emerging body of literature has indicated that broad, transdiagnostic
dimensions of psychopathology are associated with alterations in brain structure across the …

[HTML][HTML] Deviations from normative brain white and gray matter structure are associated with psychopathology in youth

R Kjelkenes, T Wolfers, D Alnæs, LB Norbom… - Developmental …, 2022 - Elsevier
Combining imaging modalities and metrics that are sensitive to various aspects of brain
structure and maturation may help identify individuals that show deviations in relation to …