Fungal pathogens cause significant human morbidity and mortality globally, where there is a
propensity to infect vulnerable people such as the immunocompromised ones. There is …

Antifungal resistance in humans, animals, and the environment is an emerging problem.
Among the different fungal species that can develop resistance, Candida tropicalis is …

Background Fosmanogepix is a first-in-class antifungal targeting the fungal enzyme Gwt1,
with broad-spectrum activity against yeasts and moulds, including multidrug-resistant fungi …

Candidemia remains a major public health challenge due to its high mortality rates,
especially in developing countries. Monitoring epidemiological trends may provide insights …

Candida is the most prevalent fungal bloodstream infection (BSI) with a high mortality rate
among hospitalized patients. Another concern facing physicians is rising global incidence of …

Background This study was designed to determine changes in risk factors on the prognosis
of patients during each period of the bloodstream infection (BSI) timeline. Methods Through …

The gold standard for diagnosing invasive candidiasis still relies on blood cultures, which
are inefficient and time-consuming to analyze. We developed an in-house qPCR assay to …

Candidemia is one of the healthcare-associated infections that has high mortality. The risk
factors that predispose a patient to develop this infection are mostly found in patients of …

Background The natural history of candidemia in kidney transplant recipients (KTR) remains
poorly understood. This study aimed to evaluate mortality, prognostic factors and overall …

Candidemia is a significant cause of mortality among hospitalized patients, both worldwide
and in Brazil. Prompt and appropriate treatment are essential to mitigate mortality, and …