[HTML][HTML] Mechanisms of SARS-CoV-2 transmission and pathogenesis

AG Harrison, T Lin, P Wang - Trends in immunology, 2020 - cell.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marks
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …

From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses

N Kirtipal, S Bharadwaj, SG Kang - Infection, Genetics and Evolution, 2020 - Elsevier
Abstract Human Coronaviruses (HCoV), periodically emerging across the world, are
potential threat to humans such as severe acute respiratory syndrome coronavirus-2 (SARS …

[HTML][HTML] Activation and evasion of type I interferon responses by SARS-CoV-2

X Lei, X Dong, R Ma, W Wang, X Xiao, Z Tian… - Nature …, 2020 - nature.com
The pandemic of COVID-19 has posed an unprecedented threat to global public health.
However, the interplay between the viral pathogen of COVID-19, SARS-CoV-2, and host …

[HTML][HTML] IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

R Channappanavar, AR Fehr, J Zheng… - The Journal of …, 2019 - Am Soc Clin Investig
Type 1 IFNs (IFN-I) generally protect mammalian hosts from virus infections, but in some
cases, IFN-I is pathogenic. Because IFN-I is protective, it is commonly used to treat virus …

[HTML][HTML] Inhibition of SARS–CoV-2 by type I and type III interferons

U Felgenhauer, A Schoen, HH Gad, R Hartmann… - Journal of Biological …, 2020 - ASBMB
The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS–CoV-2) is
the causative agent of the devastating COVID-19 lung disease pandemic. Here, we tested …

[HTML][HTML] Virus infection induced pulmonary fibrosis

WJ Huang, XX Tang - Journal of Translational Medicine, 2021 - Springer
Pulmonary fibrosis is the end stage of a broad range of heterogeneous interstitial lung
diseases and more than 200 factors contribute to it. In recent years, the relationship between …

Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus

J Zhou, C Li, G Zhao, H Chu, D Wang, HHN Yan… - Science …, 2017 - science.org
Middle East respiratory syndrome coronavirus (MERS-CoV) has caused human respiratory
infections with a high case fatality rate since 2012. However, the mode of virus transmission …

Middle East respiratory syndrome

A Zumla, DS Hui, S Perlman - The Lancet, 2015 - thelancet.com
Middle East respiratory syndrome (MERS) is a highly lethal respiratory disease caused by a
novel single-stranded, positive-sense RNA betacoronavirus (MERS-CoV). Dromedary …

Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease

JFW Chan, SKP Lau, KKW To… - Clinical microbiology …, 2015 - Am Soc Microbiol
The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife
market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led …

Middle East respiratory syndrome coronavirus (MERS‐CoV): infection, immunological response, and vaccine development

A Mubarak, W Alturaiki… - Journal of immunology …, 2019 - Wiley Online Library
Middle East respiratory syndrome coronavirus (MERS‐CoV) first emerged in late 2012.
Since its emergence, a total of 2279 patients from 27 countries have been infected across …