Drosophila melanogaster: A platform for anticancer drug discovery and personalized therapies
C Munnik, MP Xaba, ST Malindisa, BL Russell… - Frontiers in …, 2022 - frontiersin.org
Cancer is a complex disease whereby multiple genetic aberrations, epigenetic
modifications, metabolic reprogramming, and the microenvironment contribute to the …
modifications, metabolic reprogramming, and the microenvironment contribute to the …
Drosophila as a toolkit to tackle cancer and its metabolism
H Jiang, T Kimura, H Hai, R Yamamura… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most severe health problems worldwide accounting for the second
leading cause of death. Studies have indicated that cancers utilize different metabolic …
leading cause of death. Studies have indicated that cancers utilize different metabolic …
Navigating multi-scale cancer systems biology towards model-driven clinical oncology and its applications in personalized therapeutics
MN Gondal, SU Chaudhary - Frontiers in Oncology, 2021 - frontiersin.org
Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
Combined cytotoxic effect of inhibitors of proteostasis on human colon cancer cells
AD Nikotina, SA Vladimirova, NE Kokoreva… - Pharmaceuticals, 2022 - mdpi.com
Despite significant progress in the diagnosis and treatment of colorectal cancer, drug
resistance continues to be a major limitation of therapy. In this regard, studies aimed at …
resistance continues to be a major limitation of therapy. In this regard, studies aimed at …
Classification of molecular subtypes for colorectal cancer and development of a prognostic model based on necroptosis-related genes
M Li, M Lu, J Li, Q Gui, Y Xia, C Lu, H Shu - Heliyon, 2024 - cell.com
Background Necroptosis could regulate immunity in cancers, and stratification of colorectal
cancer (CRC) subtypes based on key genes related to necroptosis might be a novel strategy …
cancer (CRC) subtypes based on key genes related to necroptosis might be a novel strategy …
[HTML][HTML] Fruit fly for anticancer drug discovery and repurposing
In 2020, around one of six deaths was attributed to cancer-related diseases, making cancer
as one of the leading causes of mortality worldwide 1. Cancer is a complex multifaceted …
as one of the leading causes of mortality worldwide 1. Cancer is a complex multifaceted …
CanSeer: A Method for Development and Clinical Translation of Personalized Cancer Therapeutics
RN Butt, B Amina, MU Sultan, ZB Tanveer, R Hussain… - bioRxiv, 2022 - biorxiv.org
Computational modeling and analysis of biomolecular network models annotated with
cancer patient-specific multi-omics data can enable the development of personalized …
cancer patient-specific multi-omics data can enable the development of personalized …