This study aimed to investigate the controversial association between metformin use and
diabetes-associated dementia in elderly patients with type 2 diabetes mellitus (T2DM) and …

Objective To investigate risks of multiple adverse outcomes associated with use of
antipsychotics in people with dementia. Design Population based matched cohort study …

The abnormal amyloid‐β accumulation is essential and obbligato in Alzheimer's disease
pathogenesis and natural polyphenols exhibit great potential as amyloid aggregation …

Alzheimer's disease (AD) is a highly damaging disease that affects one's cognition and
memory and presents an increasing societal and economic burden globally. Considerable …

Alzheimer's disease (AD) is the most common form of dementia without effective clinical
treatment. Here, we show that intermittent fasting (IF) improves cognitive functions and AD …

Background Reducing the intake of total fat, saturated fatty acids (SFA) and dietary
cholesterol was a cornerstone of dietary guidance in past decades. This emphasis shifted …

The recent biological redefinition of Alzheimer's Disease (AD) has spurred the development
of statistical models that relate changes in biomarkers with neurodegeneration and …

Importance Sleep disturbances and clinical sleep disorders are associated with all-cause
dementia and neurodegenerative conditions, but it remains unclear how longitudinal …

Abstract Background Both Alzheimer's disease (AD) genetic risk factors and indices of
cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether …

Background Social isolation is prevalent and associated with dementia, yet the directionality
and mechanisms are less understood. This study examined the association between social …